Effect of Adhatoda vasica leaf powder as herbal feed additive on growth performance and biochemical parameters of serum and liver of broilers

K. Kannan, R. Mathivanan, M. G. Sudha, B. Sokkalingam, R. Balagopal, R. Velazhahan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Adhatoda vasica (L.) Nees leaf extract has been reported to have aflatoxin detoxifying properties and hepatoprotective effect on aflatoxin B1-induced liver damage in Wistar rats. This medicinal plant can be added to broiler diets as feed additives to reduce the toxic effects of aflatoxin in feeds. However, several reports indicate that alkaloids containing plants are toxic to broilers. Hence, an experiment was conducted to evaluate the effect of A. vasica on growth performance and biochemical parameters in serum and liver of broiler chicks (VenCobb 400). The treatments consisted of basal diet (control), basal diet supplemented with 0.5%, 1%, 1.5% and 2% of A. vasica leaf powder. The results suggest that feed intake and body weight gain were not significantly affected by dietary supplementation of A. vasica leaf powder up to 1.5% level when compared with the control feed. The best feed conversion ratio (1.66) was observed in the group fed with 1.5% of A. vasica leaf powder. No significant differences were observed in the levels of hemoglobin, red blood cells, packed cell volume, glucose and cholesterol in the serum of broiler chickens due to dietary supplementation of A. vasica powder when compared to control. An increase in Glutathione (GSH) and Glutathione S- transferase (GST) activities were observed in the A. vasica fed groups when compared to the control group. The results suggest that A. vasica could be considered as a potential and safe herbal feed additive for broilers to counteract the toxic effect of aflatoxins.

Original languageEnglish
Pages (from-to)407-413
Number of pages7
JournalBiochemical and Cellular Archives
Volume17
Issue number1
Publication statusPublished - 2017

Fingerprint

Justicia
Liver
Powders
Aflatoxins
Poisons
Nutrition
Growth
Serum
Aflatoxin B1
Dietary Supplements
Diet
Glutathione Transferase
Alkaloids
Glutathione
Rats
Hemoglobins
Blood
Cholesterol
Cells
Toxic Plants

Keywords

  • Adhatoda vasica
  • Antioxidants
  • Broiler chicken
  • Growth performance
  • Medicinal plant

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology

Cite this

Effect of Adhatoda vasica leaf powder as herbal feed additive on growth performance and biochemical parameters of serum and liver of broilers. / Kannan, K.; Mathivanan, R.; Sudha, M. G.; Sokkalingam, B.; Balagopal, R.; Velazhahan, R.

In: Biochemical and Cellular Archives, Vol. 17, No. 1, 2017, p. 407-413.

Research output: Contribution to journalArticle

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