Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India

J. Panicker, S. Sinha, A. Taly, A. Mahadevan, C. Sagar, S. Srikanth, G. Arunodaya, S. Shankar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 37-year-old gentleman presented with macrocephaly since early childhood and progressive impairment of motor and cognitive functions. Magnetic resonance imaging revealed extensive white matter involvement and frontotemporal subcortical cysts. Absent ankle jerk and abnormal nerve conduction study raised a possibility of associated peripheral neuropathy. Sural nerve biopsy was suggestive of dysmyelinating neuropathy. This report serves to expand the clinical spectrum of this rare leukodystrophy.

Original languageEnglish
Pages (from-to)399-402
Number of pages4
JournalNeurology India
Volume55
Issue number4
Publication statusPublished - Oct 1 2007

Fingerprint

Megalencephaly
Sural Nerve
Neural Conduction
Peripheral Nervous System Diseases
Ankle
Cognition
Cysts
India
Magnetic Resonance Imaging
Observation
Biopsy
White Matter
Megalencephalic leukoencephalopathy with subcortical cysts

Keywords

  • Benign leukodystrophy; dysmyelinating neuropathy; leukoencephalopathy with subcortical cysts
  • Megalencephalic

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Panicker, J., Sinha, S., Taly, A., Mahadevan, A., Sagar, C., Srikanth, S., ... Shankar, S. (2007). Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India. Neurology India, 55(4), 399-402.

Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts : A novel observation from south India. / Panicker, J.; Sinha, S.; Taly, A.; Mahadevan, A.; Sagar, C.; Srikanth, S.; Arunodaya, G.; Shankar, S.

In: Neurology India, Vol. 55, No. 4, 01.10.2007, p. 399-402.

Research output: Contribution to journalArticle

Panicker, J, Sinha, S, Taly, A, Mahadevan, A, Sagar, C, Srikanth, S, Arunodaya, G & Shankar, S 2007, 'Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India', Neurology India, vol. 55, no. 4, pp. 399-402.
Panicker, J. ; Sinha, S. ; Taly, A. ; Mahadevan, A. ; Sagar, C. ; Srikanth, S. ; Arunodaya, G. ; Shankar, S. / Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts : A novel observation from south India. In: Neurology India. 2007 ; Vol. 55, No. 4. pp. 399-402.
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