Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India

J. Panicker; S. Sinha; A. Taly; A. Mahadevan; C. Sagar; S. Srikanth; G. Arunodaya; S. Shankar

doi:10.4103/0028-3886.33310

Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India

J. Panicker, S. Sinha^*, A. Taly, A. Mahadevan, C. Sagar, S. Srikanth, G. Arunodaya, S. Shankar

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A 37-year-old gentleman presented with macrocephaly since early childhood and progressive impairment of motor and cognitive functions. Magnetic resonance imaging revealed extensive white matter involvement and frontotemporal subcortical cysts. Absent ankle jerk and abnormal nerve conduction study raised a possibility of associated peripheral neuropathy. Sural nerve biopsy was suggestive of dysmyelinating neuropathy. This report serves to expand the clinical spectrum of this rare leukodystrophy.

Original language	English
Pages (from-to)	399-402
Number of pages	4
Journal	Neurology India
Volume	55
Issue number	4
DOIs	https://doi.org/10.4103/0028-3886.33310
Publication status	Published - Oct 1 2007
Externally published	Yes

Keywords

Benign leukodystrophy; dysmyelinating neuropathy; leukoencephalopathy with subcortical cysts
Megalencephalic

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.4103/0028-3886.33310

Cite this

@article{4105043a981c4af69c645826bb187d23,

title = "Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India",

abstract = "A 37-year-old gentleman presented with macrocephaly since early childhood and progressive impairment of motor and cognitive functions. Magnetic resonance imaging revealed extensive white matter involvement and frontotemporal subcortical cysts. Absent ankle jerk and abnormal nerve conduction study raised a possibility of associated peripheral neuropathy. Sural nerve biopsy was suggestive of dysmyelinating neuropathy. This report serves to expand the clinical spectrum of this rare leukodystrophy.",

keywords = "Benign leukodystrophy; dysmyelinating neuropathy; leukoencephalopathy with subcortical cysts, Megalencephalic",

author = "J. Panicker and S. Sinha and A. Taly and A. Mahadevan and C. Sagar and S. Srikanth and G. Arunodaya and S. Shankar",

year = "2007",

month = oct,

day = "1",

doi = "10.4103/0028-3886.33310",

language = "English",

volume = "55",

pages = "399--402",

journal = "Neurology India",

issn = "0028-3886",

publisher = "Medknow Publications and Media Pvt. Ltd",

number = "4",

}

TY - JOUR

T1 - Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts

T2 - A novel observation from south India

AU - Panicker, J.

AU - Sinha, S.

AU - Taly, A.

AU - Mahadevan, A.

AU - Sagar, C.

AU - Srikanth, S.

AU - Arunodaya, G.

AU - Shankar, S.

PY - 2007/10/1

Y1 - 2007/10/1

N2 - A 37-year-old gentleman presented with macrocephaly since early childhood and progressive impairment of motor and cognitive functions. Magnetic resonance imaging revealed extensive white matter involvement and frontotemporal subcortical cysts. Absent ankle jerk and abnormal nerve conduction study raised a possibility of associated peripheral neuropathy. Sural nerve biopsy was suggestive of dysmyelinating neuropathy. This report serves to expand the clinical spectrum of this rare leukodystrophy.

AB - A 37-year-old gentleman presented with macrocephaly since early childhood and progressive impairment of motor and cognitive functions. Magnetic resonance imaging revealed extensive white matter involvement and frontotemporal subcortical cysts. Absent ankle jerk and abnormal nerve conduction study raised a possibility of associated peripheral neuropathy. Sural nerve biopsy was suggestive of dysmyelinating neuropathy. This report serves to expand the clinical spectrum of this rare leukodystrophy.

KW - Benign leukodystrophy; dysmyelinating neuropathy; leukoencephalopathy with subcortical cysts

KW - Megalencephalic

UR - http://www.scopus.com/inward/record.url?scp=36549070601&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36549070601&partnerID=8YFLogxK

U2 - 10.4103/0028-3886.33310

DO - 10.4103/0028-3886.33310

M3 - Article

C2 - 18040118

AN - SCOPUS:36549070601

SN - 0028-3886

VL - 55

SP - 399

EP - 402

JO - Neurology India

JF - Neurology India

IS - 4

ER -

Dysmyelinating neuropathy in benign form of megalencephalic leukoencephalopathy with subcortical cysts: A novel observation from south India

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this