Abstract
Middle East Respiratory Syndrome Coronavirus (MERS-CorV), was discovered in humans with lower respiratory tract infection, causes a range of illnesses in humans, from the common cold to the Severe Acute Respiratory Syndrome (SARS). Scientists give much attention to study the CorV infection among groups and travelers. In this paper, we utilize a mathematical model governed by a system of differential equations, which incorporate target cell limitation and the innate interferon response, investigate the innate and adaptive immune responses to primary CorV infection in an individual. We also investigate the sensitivity analysis of the model to determine the most sensitive parameters and informative subintervals. This study may promote clearance of virus and host recovery from infection.
Original language | English |
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Title of host publication | Mathematical Methods and Computational Techniques in Science and Engineering II |
Editors | Nikos Bardis |
Publisher | American Institute of Physics Inc. |
Volume | 1982 |
ISBN (Electronic) | 9780735416987 |
DOIs | |
Publication status | Published - Jul 27 2018 |
Event | 2nd International Conference on Mathematical Methods and Computational Techniques in Science and Engineering - Cambridge, United Kingdom Duration: Feb 16 2018 → Feb 18 2018 |
Other
Other | 2nd International Conference on Mathematical Methods and Computational Techniques in Science and Engineering |
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Country | United Kingdom |
City | Cambridge |
Period | 2/16/18 → 2/18/18 |
Keywords
- Coronavirus
- Immunological barrier
- Infectious disease
- Mathematical modeling; Sensitivity
ASJC Scopus subject areas
- Physics and Astronomy(all)