Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles

Issam M. Bahadur, Christopher Yee Wong, Xinggang Jiang, James K. Mills

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this paper, the nonlinear three-dimensional dynamics of a micro-needle driven at ultrasonic operating frequencies is briefly derived. The micro-needle is simulated as an Euler-Bernoulli cantilever beam attached to a moving base. The equations of motion of cutting micro-needle are derived with Kane's method. The shear and rotary inertia effects are neglected by considering a slender-shaped beam with homogeneous and isotropic material properties. Furthermore, the elastic and centroidal axes of the cross-section of the micro-needle coincide so that eccentricity effects are not considered. The micro-needle is modelled with contact with an embryo zone pellucida, submerged in a fluid medium. The surrounding fluid is modeled as incompressible using the Morison equation. From the simulation model, resonant frequencies are determined. Experimental work is presented for perforation of mouse zona pellucida with the micro-needle PZT actuator driven at different frequencies. Experimental tests are conducted to determine a threshold frequency below which PZT actuated zona perforation is unsuccessful.

Original languageEnglish
Title of host publication2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages445-450
Number of pages6
ISBN (Electronic)9781509067572
DOIs
Publication statusPublished - Aug 23 2017
Event14th IEEE International Conference on Mechatronics and Automation, ICMA 2017 - Takamatsu, Japan
Duration: Aug 6 2017Aug 9 2017

Other

Other14th IEEE International Conference on Mechatronics and Automation, ICMA 2017
CountryJapan
CityTakamatsu
Period8/6/178/9/17

Fingerprint

perforation
embryos
Dynamic Modeling
Embryo
needles
Needles
Experiment
Fluid
Euler-Bernoulli Beam
Cantilever Beam
Resonant Frequency
Experiments
Eccentricity
Material Properties
Inertia
Mouse
Actuator
Equations of Motion
Simulation Model
Cross section

Keywords

  • Cell perforation
  • Dynamic modelling
  • Dynamic simulation
  • Experimental perforation
  • Piezo actuator

ASJC Scopus subject areas

  • Control and Optimization
  • Instrumentation
  • Artificial Intelligence
  • Industrial and Manufacturing Engineering
  • Mechanical Engineering

Cite this

Bahadur, I. M., Wong, C. Y., Jiang, X., & Mills, J. K. (2017). Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles. In 2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017 (pp. 445-450). [8015858] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICMA.2017.8015858

Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles. / Bahadur, Issam M.; Wong, Christopher Yee; Jiang, Xinggang; Mills, James K.

2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017. Institute of Electrical and Electronics Engineers Inc., 2017. p. 445-450 8015858.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bahadur, IM, Wong, CY, Jiang, X & Mills, JK 2017, Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles. in 2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017., 8015858, Institute of Electrical and Electronics Engineers Inc., pp. 445-450, 14th IEEE International Conference on Mechatronics and Automation, ICMA 2017, Takamatsu, Japan, 8/6/17. https://doi.org/10.1109/ICMA.2017.8015858
Bahadur IM, Wong CY, Jiang X, Mills JK. Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles. In 2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017. Institute of Electrical and Electronics Engineers Inc. 2017. p. 445-450. 8015858 https://doi.org/10.1109/ICMA.2017.8015858
Bahadur, Issam M. ; Wong, Christopher Yee ; Jiang, Xinggang ; Mills, James K. / Dynamic modelling and embryo zona pellucida perforation experiments with piezoelectric actuated micro-needles. 2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 445-450
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