Abstract
In this paper, the nonlinear three-dimensional dynamics of a micro-needle driven at ultrasonic operating frequencies is briefly derived. The micro-needle is simulated as an Euler-Bernoulli cantilever beam attached to a moving base. The equations of motion of cutting micro-needle are derived with Kane's method. The shear and rotary inertia effects are neglected by considering a slender-shaped beam with homogeneous and isotropic material properties. Furthermore, the elastic and centroidal axes of the cross-section of the micro-needle coincide so that eccentricity effects are not considered. The micro-needle is modelled with contact with an embryo zone pellucida, submerged in a fluid medium. The surrounding fluid is modeled as incompressible using the Morison equation. From the simulation model, resonant frequencies are determined. Experimental work is presented for perforation of mouse zona pellucida with the micro-needle PZT actuator driven at different frequencies. Experimental tests are conducted to determine a threshold frequency below which PZT actuated zona perforation is unsuccessful.
Original language | English |
---|---|
Title of host publication | 2017 IEEE International Conference on Mechatronics and Automation, ICMA 2017 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 445-450 |
Number of pages | 6 |
ISBN (Electronic) | 9781509067572 |
DOIs | |
Publication status | Published - Aug 23 2017 |
Event | 14th IEEE International Conference on Mechatronics and Automation, ICMA 2017 - Takamatsu, Japan Duration: Aug 6 2017 → Aug 9 2017 |
Other
Other | 14th IEEE International Conference on Mechatronics and Automation, ICMA 2017 |
---|---|
Country/Territory | Japan |
City | Takamatsu |
Period | 8/6/17 → 8/9/17 |
Keywords
- Cell perforation
- Dynamic modelling
- Dynamic simulation
- Experimental perforation
- Piezo actuator
ASJC Scopus subject areas
- Control and Optimization
- Instrumentation
- Artificial Intelligence
- Industrial and Manufacturing Engineering
- Mechanical Engineering