Does pterygopalatine canal injection with local anaesthetic and adrenaline decrease bleeding during functional endoscopic sinus surgery?

C. J. Valdes, Y. Al Badaai, M. Bogado, M. Samaha

Research output: Contribution to journalArticle

11 Citations (Scopus)


Objective: To determine the effect of pterygopalatine fossa injection with xylocaine and adrenaline on: surgical field bleeding and blood loss during functional endoscopic sinus surgery for chronic rhinosinusitis, and the duration of the procedure.

Methods: A prospective, single-blinded, controlled trial was performed in a tertiary care academic centre. A total of 45 patients undergoing functional endoscopic sinus surgery for chronic rhinosinusitis, whose disease was symmetrical based on computed tomography grading, were included. A unilateral pterygopalatine fossa injection with 1 per cent xylocaine and 1:100 000 adrenaline was performed after the induction of anaesthesia. The contralateral side served as the control. The operating surgeon, who was blinded to the injected side, assessed the surgical field using a validated six-item grading system. Blood loss, blood pressure, heart rate and end-tidal carbon dioxide were recorded every 15 minutes for each side separately, and duration of surgery was noted.

Results: There was no statistically significant difference in the surgical field grade between the injected and non-injected sides (p = 0.161). There were no differences in blood loss or duration of surgery.

Conclusion: Pterygopalatine fossa injection prior to functional endoscopic sinus surgery did not decrease intra-operative surgical field bleeding, blood loss or duration of surgery.

Original languageEnglish
Pages (from-to)814-817
Number of pages4
JournalJournal of Laryngology and Otology
Issue number9
Publication statusPublished - Sep 14 2014



  • Hemorrhage
  • Nasal Surgical Procedures
  • Pterygopalatine Fossa
  • Vasoconstrictor Agents

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

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