Abstract
Abstract: The synthesis of a novel series of 5-fluoro-6-(4-methylpiperazin-1-yl)-substituted phenylbenzo[d]thiazoles is reported. These molecules have been screened against different bacteria and fungi strains. Among these, two compounds show excellent bacterial growth inhibition against Gram-positive bacteria Staphylococcus aureus with MIC 32 μg/cm3 compared to tamoxifen used as a positive standard. Graphical abstract: [Figure not available: see fulltext.].
Original language | English |
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Pages (from-to) | 645-651 |
Number of pages | 7 |
Journal | Monatshefte fur Chemie |
Volume | 149 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 1 2018 |
Keywords
- 2-Arylbenzothiazole
- Antimicrobial
- Fluorine
- Piperazine
ASJC Scopus subject areas
- General Chemistry