Dengue fever complicated by hemophagocytosis

Maria Koshy, Ajay Kumar Mishra, Bhumi Agrawal, Akhil Rajendra Kurup, Samuel George Hansdak

Research output: Contribution to journalComment/debate

8 Citations (Scopus)

Abstract

Dengue is acommon acute viral febrile illness in the tropics. Although the usual presentation is that of a self-limiting illness, its complications are protean. We report a 29-year-old man who presented with an acute febrile illness and was diagnosed with dengue hemorrhagic fever. Despite appropriate supportive therapy, the patient initially improved, but subsequently had clinical deterioration. Evaluation revealed features of hemophagocytic lymphohistiocytosis. He was successfully treated with glucocorticoids and had an uneventful recovery. This case adds to the limited adult cases of virus-associated hemophagocytic syndrome in the literature and the need for prompt recognition and treatment of this rare complication.

Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalOxford Medical Case Reports
Volume2016
Issue number6
DOIs
Publication statusPublished - 2016

Fingerprint

Hemophagocytic Lymphohistiocytosis
Dengue
Fever
Severe Dengue
Glucocorticoids
Viruses
Therapeutics

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Infectious Diseases

Cite this

Dengue fever complicated by hemophagocytosis. / Koshy, Maria; Mishra, Ajay Kumar; Agrawal, Bhumi; Kurup, Akhil Rajendra; Hansdak, Samuel George.

In: Oxford Medical Case Reports, Vol. 2016, No. 6, 2016, p. 121-124.

Research output: Contribution to journalComment/debate

Koshy, M, Mishra, AK, Agrawal, B, Kurup, AR & Hansdak, SG 2016, 'Dengue fever complicated by hemophagocytosis', Oxford Medical Case Reports, vol. 2016, no. 6, pp. 121-124. https://doi.org/10.1093/omcr/omw043
Koshy, Maria ; Mishra, Ajay Kumar ; Agrawal, Bhumi ; Kurup, Akhil Rajendra ; Hansdak, Samuel George. / Dengue fever complicated by hemophagocytosis. In: Oxford Medical Case Reports. 2016 ; Vol. 2016, No. 6. pp. 121-124.
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