Demographic and clinical characteristics of type 1 diabetes mellitus in omani children - single center experience

Saif Al-Yaarubi, Irfan Ullah, Sharef Waadallah Sharef, Azza Al Shidhani, Shaima Al Hanai, Rab'aa Al Kalbani, Shamsa Al Jamoodi

Research output: Contribution to journalArticle

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Abstract

Objectives: To describe the demographic characteristics and clinical presentation of Omani children with type 1 diabetes mellitus at Sultan Qaboos University Hospital, Muscat, Oman. Methods: A retrospective analysis of all children with type 1 diabetes mellitus attending the Pediatric Endocrine Unit at Sultan Qaboos University Hospital, Oman from June 2006 to May 2013. Results: One hundred and forty-four patients were included in the study. The mean±SD of age at diagnosis was 6.7 ± 3.7 years. The median duration of symptoms was 10 days (IQR; 5-14). The most commonly reported presenting symptoms were polyuria (94%), polydipsia (82%), and weight loss (59%). Diabetic ketoacidosis at initial presentation was diagnosed in 31% of the patients. Different insulin regimens were prescribed: multiple daily injections in 109 (76%) patients, twice daily insulin regimen in 23 (16%) patients, and insulin pump therapy in 12 (8%) patients. Family history of type 1 diabetes mellitus was present in 31 (22%) patients. There were no significant differences in presenting complaints (polyuria, p=0.182; polydipsia, p=0.848), duration of symptoms (p=0.331), reported weight loss (p=0.753), or diabetic ketoacidosis at presentation (p=0.608) between patients with and without family history of type 1 diabetes mellitus. Conclusion: Polyuria, polydipsia and weight loss are the most common presenting symptoms. Family history of type 1 diabetes mellitus is highly prevalent among the studied patients. Diabetic ketoacidosis was found to be less common in Oman compared to other diabetes centers in the Middle East.

Original languageEnglish
Pages (from-to)119-122
Number of pages4
JournalOman Medical Journal
Volume29
Issue number2
DOIs
Publication statusPublished - 2014

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Type 1 Diabetes Mellitus
Demography
Oman
Polydipsia
Polyuria
Diabetic Ketoacidosis
Weight Loss
Insulin
Middle East
Pediatrics
Injections

Keywords

  • Children
  • Diabetic ketoacidosis (DKA)
  • Family history
  • Insulin
  • Oman
  • Type 1 diabetes mellitus (T1DM)

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Demographic and clinical characteristics of type 1 diabetes mellitus in omani children - single center experience. / Al-Yaarubi, Saif; Ullah, Irfan; Sharef, Sharef Waadallah; Al Shidhani, Azza; Al Hanai, Shaima; Al Kalbani, Rab'aa; Al Jamoodi, Shamsa.

In: Oman Medical Journal, Vol. 29, No. 2, 2014, p. 119-122.

Research output: Contribution to journalArticle

Al-Yaarubi, Saif ; Ullah, Irfan ; Sharef, Sharef Waadallah ; Al Shidhani, Azza ; Al Hanai, Shaima ; Al Kalbani, Rab'aa ; Al Jamoodi, Shamsa. / Demographic and clinical characteristics of type 1 diabetes mellitus in omani children - single center experience. In: Oman Medical Journal. 2014 ; Vol. 29, No. 2. pp. 119-122.
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AU - Al Jamoodi, Shamsa

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N2 - Objectives: To describe the demographic characteristics and clinical presentation of Omani children with type 1 diabetes mellitus at Sultan Qaboos University Hospital, Muscat, Oman. Methods: A retrospective analysis of all children with type 1 diabetes mellitus attending the Pediatric Endocrine Unit at Sultan Qaboos University Hospital, Oman from June 2006 to May 2013. Results: One hundred and forty-four patients were included in the study. The mean±SD of age at diagnosis was 6.7 ± 3.7 years. The median duration of symptoms was 10 days (IQR; 5-14). The most commonly reported presenting symptoms were polyuria (94%), polydipsia (82%), and weight loss (59%). Diabetic ketoacidosis at initial presentation was diagnosed in 31% of the patients. Different insulin regimens were prescribed: multiple daily injections in 109 (76%) patients, twice daily insulin regimen in 23 (16%) patients, and insulin pump therapy in 12 (8%) patients. Family history of type 1 diabetes mellitus was present in 31 (22%) patients. There were no significant differences in presenting complaints (polyuria, p=0.182; polydipsia, p=0.848), duration of symptoms (p=0.331), reported weight loss (p=0.753), or diabetic ketoacidosis at presentation (p=0.608) between patients with and without family history of type 1 diabetes mellitus. Conclusion: Polyuria, polydipsia and weight loss are the most common presenting symptoms. Family history of type 1 diabetes mellitus is highly prevalent among the studied patients. Diabetic ketoacidosis was found to be less common in Oman compared to other diabetes centers in the Middle East.

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KW - Diabetic ketoacidosis (DKA)

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KW - Insulin

KW - Oman

KW - Type 1 diabetes mellitus (T1DM)

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