DAT1 VNTR allele frequencies in the Omani population

M. Simsek, K. Lawatia, S. Al-Adawi, M. Al-Sharbati

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The frequency of the observed genotypes was not significantly different from the expected Hardy-Weinberg distribution. We compared the Omani DAT1 alleles with similar data from other populations.

Original languageEnglish
Pages (from-to)281-286
Number of pages6
JournalHuman Biology
Volume77
Issue number2
Publication statusPublished - Apr 2005

Keywords

  • DAT1
  • Dopamine transporter gene
  • Oman
  • Polymorphism
  • VNTR

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)
  • Ecology, Evolution, Behavior and Systematics

Fingerprint Dive into the research topics of 'DAT1 VNTR allele frequencies in the Omani population'. Together they form a unique fingerprint.

  • Cite this

    Simsek, M., Lawatia, K., Al-Adawi, S., & Al-Sharbati, M. (2005). DAT1 VNTR allele frequencies in the Omani population. Human Biology, 77(2), 281-286.