Abstract
To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The frequency of the observed genotypes was not significantly different from the expected Hardy-Weinberg distribution. We compared the Omani DAT1 alleles with similar data from other populations.
Original language | English |
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Pages (from-to) | 281-286 |
Number of pages | 6 |
Journal | Human Biology |
Volume | 77 |
Issue number | 2 |
Publication status | Published - Apr 2005 |
Keywords
- DAT1
- Dopamine transporter gene
- Oman
- Polymorphism
- VNTR
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Genetics
- Genetics(clinical)