DAT1 VNTR allele frequencies in the Omani population

M. Simsek, K. Lawatia, S. Al-Adawi, M. Al-Sharbati

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To determine the genetic variability at the human DAT1 VNTR locus, we screened 110 healthy Omani blood donors using the polymerase chain reaction (PCR) and agarose gel electrophoresis. Two common alleles (DAT1*9 and DAT1*10) were observed with a frequency of 0.332 and 0.609, respectively. There were also five rare alleles (*3, *6, *7, *8, and *11). The frequency of the observed genotypes was not significantly different from the expected Hardy-Weinberg distribution. We compared the Omani DAT1 alleles with similar data from other populations.

Original languageEnglish
Pages (from-to)281-286
Number of pages6
JournalHuman Biology
Volume77
Issue number2
Publication statusPublished - Apr 2005

Fingerprint

minisatellite repeats
Gene Frequency
gene frequency
allele
Alleles
alleles
Population
Minisatellite Repeats
Agar Gel Electrophoresis
Blood Donors
agarose
polymerase chain reaction
gel electrophoresis
electrokinesis
genotype
gel
blood
Genotype
Polymerase Chain Reaction
genetic variation

Keywords

  • DAT1
  • Dopamine transporter gene
  • Oman
  • Polymorphism
  • VNTR

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)
  • Ecology, Evolution, Behavior and Systematics

Cite this

Simsek, M., Lawatia, K., Al-Adawi, S., & Al-Sharbati, M. (2005). DAT1 VNTR allele frequencies in the Omani population. Human Biology, 77(2), 281-286.

DAT1 VNTR allele frequencies in the Omani population. / Simsek, M.; Lawatia, K.; Al-Adawi, S.; Al-Sharbati, M.

In: Human Biology, Vol. 77, No. 2, 04.2005, p. 281-286.

Research output: Contribution to journalArticle

Simsek, M, Lawatia, K, Al-Adawi, S & Al-Sharbati, M 2005, 'DAT1 VNTR allele frequencies in the Omani population', Human Biology, vol. 77, no. 2, pp. 281-286.
Simsek M, Lawatia K, Al-Adawi S, Al-Sharbati M. DAT1 VNTR allele frequencies in the Omani population. Human Biology. 2005 Apr;77(2):281-286.
Simsek, M. ; Lawatia, K. ; Al-Adawi, S. ; Al-Sharbati, M. / DAT1 VNTR allele frequencies in the Omani population. In: Human Biology. 2005 ; Vol. 77, No. 2. pp. 281-286.
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