Abstract
Reaction of each member of a series of variously substituted N-(2-hydroxybenzyl)glycinate (hbg 2-) ligands [5-bromo- (5-Br-hbg 2-); 5-chloro- (5-Cl-hbg 2-); 3,5-dichloro- (3,5-Cl 2-hbg 2-); 5-chloro-3-methyl- (5,3-Cl,Me-hbg 2-); and 3,5-dimethyl- (3,5-Me 2-hbg 2-)] with cobalt(II) in stoichiometric amounts under ambient conditions afforded the Co III complex anions of the general formulatrans,trans,trans-[Co(hbg) 2] -. Single-crystal X-ray analyses of [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Cl 2-hbg) 2]3 and [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Me 2-hbg) 2]5 {[C 5H 10- NH 2] piperidinium counter ion} have revealed similar structural motifs of these compounds. Each of the crystal structures shows two non-equivalent complex anions in the unit cell connected through hydrogen bondingvia the piperidinium cation. The two hbg 2- ligands in each complex ion are arranged facially around the cobalt(III) ion and each ligand employs a phenolate oxygen, an amine nitrogen and a carboxylate oxygen to form a distorted octahedral geometry with C i symmetry. These compounds (1-5) serve as spectroscopic models for the interaction of cobalt(III) with tyrosinate ligands. The electronic spectrum of the compound [C 5H 10NH 2]-trans,trans,trans-[Co(5,3-Cl, Me-hbg) 2]4 bears a striking resemblance to that of the complex of cobalt(III) with bovine serum transferrin, [Co 2BTf]. In contrast to previous studies on the spectroscopy of the transferrins, one of the two ligand-field transitions expected to occur in [Co 2BTf] is evident in the electronic spectrum of this derivative of bovine serum transferrin in vitro. One of the fascinating characteristics of thetrans,trans,trans-[Co(hbg) 2] - model system is the solvent dependence of the optical spectra.
| Original language | English |
|---|---|
| Pages (from-to) | 4064-4069 |
| Number of pages | 6 |
| Journal | Journal of the Chemical Society, Dalton Transactions |
| Issue number | 21 |
| Publication status | Published - 2002 |
Fingerprint
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Complexes of cobalt(III) with phenolate-containing polydentate ligands and bovine serum apo-transferrin : Towards creating spectroscopic models for cobalt(III)-tyrosinate interactions. / Shongwe, Musa S.; Al-Hatmi, Said K M; Marques, Helder M.; Smith, Rachel; Nukada, Ryoji; Mikuriya, Masahiro.
In: Journal of the Chemical Society, Dalton Transactions, No. 21, 2002, p. 4064-4069.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Complexes of cobalt(III) with phenolate-containing polydentate ligands and bovine serum apo-transferrin
T2 - Towards creating spectroscopic models for cobalt(III)-tyrosinate interactions
AU - Shongwe, Musa S.
AU - Al-Hatmi, Said K M
AU - Marques, Helder M.
AU - Smith, Rachel
AU - Nukada, Ryoji
AU - Mikuriya, Masahiro
PY - 2002
Y1 - 2002
N2 - Reaction of each member of a series of variously substituted N-(2-hydroxybenzyl)glycinate (hbg 2-) ligands [5-bromo- (5-Br-hbg 2-); 5-chloro- (5-Cl-hbg 2-); 3,5-dichloro- (3,5-Cl 2-hbg 2-); 5-chloro-3-methyl- (5,3-Cl,Me-hbg 2-); and 3,5-dimethyl- (3,5-Me 2-hbg 2-)] with cobalt(II) in stoichiometric amounts under ambient conditions afforded the Co III complex anions of the general formulatrans,trans,trans-[Co(hbg) 2] -. Single-crystal X-ray analyses of [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Cl 2-hbg) 2]3 and [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Me 2-hbg) 2]5 {[C 5H 10- NH 2] piperidinium counter ion} have revealed similar structural motifs of these compounds. Each of the crystal structures shows two non-equivalent complex anions in the unit cell connected through hydrogen bondingvia the piperidinium cation. The two hbg 2- ligands in each complex ion are arranged facially around the cobalt(III) ion and each ligand employs a phenolate oxygen, an amine nitrogen and a carboxylate oxygen to form a distorted octahedral geometry with C i symmetry. These compounds (1-5) serve as spectroscopic models for the interaction of cobalt(III) with tyrosinate ligands. The electronic spectrum of the compound [C 5H 10NH 2]-trans,trans,trans-[Co(5,3-Cl, Me-hbg) 2]4 bears a striking resemblance to that of the complex of cobalt(III) with bovine serum transferrin, [Co 2BTf]. In contrast to previous studies on the spectroscopy of the transferrins, one of the two ligand-field transitions expected to occur in [Co 2BTf] is evident in the electronic spectrum of this derivative of bovine serum transferrin in vitro. One of the fascinating characteristics of thetrans,trans,trans-[Co(hbg) 2] - model system is the solvent dependence of the optical spectra.
AB - Reaction of each member of a series of variously substituted N-(2-hydroxybenzyl)glycinate (hbg 2-) ligands [5-bromo- (5-Br-hbg 2-); 5-chloro- (5-Cl-hbg 2-); 3,5-dichloro- (3,5-Cl 2-hbg 2-); 5-chloro-3-methyl- (5,3-Cl,Me-hbg 2-); and 3,5-dimethyl- (3,5-Me 2-hbg 2-)] with cobalt(II) in stoichiometric amounts under ambient conditions afforded the Co III complex anions of the general formulatrans,trans,trans-[Co(hbg) 2] -. Single-crystal X-ray analyses of [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Cl 2-hbg) 2]3 and [C 5H 10NH 2]-trans,trans,trans-[Co(3,5-Me 2-hbg) 2]5 {[C 5H 10- NH 2] piperidinium counter ion} have revealed similar structural motifs of these compounds. Each of the crystal structures shows two non-equivalent complex anions in the unit cell connected through hydrogen bondingvia the piperidinium cation. The two hbg 2- ligands in each complex ion are arranged facially around the cobalt(III) ion and each ligand employs a phenolate oxygen, an amine nitrogen and a carboxylate oxygen to form a distorted octahedral geometry with C i symmetry. These compounds (1-5) serve as spectroscopic models for the interaction of cobalt(III) with tyrosinate ligands. The electronic spectrum of the compound [C 5H 10NH 2]-trans,trans,trans-[Co(5,3-Cl, Me-hbg) 2]4 bears a striking resemblance to that of the complex of cobalt(III) with bovine serum transferrin, [Co 2BTf]. In contrast to previous studies on the spectroscopy of the transferrins, one of the two ligand-field transitions expected to occur in [Co 2BTf] is evident in the electronic spectrum of this derivative of bovine serum transferrin in vitro. One of the fascinating characteristics of thetrans,trans,trans-[Co(hbg) 2] - model system is the solvent dependence of the optical spectra.
UR - http://www.scopus.com/inward/record.url?scp=0036026807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036026807&partnerID=8YFLogxK
M3 - Article
SP - 4064
EP - 4069
JO - Dalton Transactions
JF - Dalton Transactions
SN - 0300-9246
IS - 21
ER -