Co-occurrence of Wilson's disease and glioblastoma multiforme - Is it a chance association?

S. Sinha, L. K. Prashanth, A. Mahadevan, S. Satish, S. Ravishankar, G. R. Arunodaya, A. B. Taly, S. K. Shankar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report a patient with glioblastoma multiforme who was subsequently diagnosed to have Wilson's disease. Immunohistochemical studies of the tumor revealed high (> 60%) labeling index for p53 and Rb retinoblastoma protein. Whether this association is like the co-occurrence of retinoblastoma and Wilson's disease due to possible somatic mutation in chromosome 13 needs to be explored.

Original languageEnglish
Pages (from-to)241-244
Number of pages4
JournalClinical Neuropathology
Volume23
Issue number5
Publication statusPublished - Sep 2004

Keywords

  • Glioblastoma multiforme
  • Malignancy
  • p53
  • Rb protein
  • Wilson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Neuroscience(all)

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  • Cite this

    Sinha, S., Prashanth, L. K., Mahadevan, A., Satish, S., Ravishankar, S., Arunodaya, G. R., Taly, A. B., & Shankar, S. K. (2004). Co-occurrence of Wilson's disease and glioblastoma multiforme - Is it a chance association? Clinical Neuropathology, 23(5), 241-244.