Abstract
We report a patient with glioblastoma multiforme who was subsequently diagnosed to have Wilson's disease. Immunohistochemical studies of the tumor revealed high (> 60%) labeling index for p53 and Rb retinoblastoma protein. Whether this association is like the co-occurrence of retinoblastoma and Wilson's disease due to possible somatic mutation in chromosome 13 needs to be explored.
| Original language | English |
|---|---|
| Pages (from-to) | 241-244 |
| Number of pages | 4 |
| Journal | Clinical Neuropathology |
| Volume | 23 |
| Issue number | 5 |
| Publication status | Published - Sept 2004 |
| Externally published | Yes |
Keywords
- Glioblastoma multiforme
- Malignancy
- Rb protein
- Wilson's disease
- p53
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Neurology
- Clinical Neurology