Clinical features of Behçet's disease in patients in the Sultanate of Oman; the significance of antiphospholipid antibodies?

E. M. El-Ageb, M. H. Al-Maini, A. K. Al-Shukaily, Y. Al-Farsi, E. R. Richens*

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The prevalence of symptoms in 34 Omani patients with Behçet's disease (BD) was: recurrent oral ulceration 100%, arthritis/arthralgia and genital ulceration 74% each, folliculitis 64%, neurological lesions 62%, retinal vasculitis 30%, iritis and hypopyon 26%, gastrointestinal lesions 12%, venous thrombosis and cardiovascular lesions 9% each, and pleuropulmonary lesions and epididymitis 6% each. Antiphospholipid (APL) antibodies (both anticardiolipin [ACAs] and anti-β2 glycoprotein I [aβ2GPIs]) were present in 11/34 (32%) of the BD patients and in 54/73 (74%) of Omani patients with systemic lupus erythematosus (SLE) (x2=21.2, P2=3.8, P=0.05). The frequency of organ involvement was similar in patients with and without APL antibodies (x2=1.226, P>0.05). This study fails to demonstrate a pathognomonic role for APL antibodies in BD.

Original languageEnglish
Pages (from-to)176-181
Number of pages6
JournalRheumatology International
Volume21
Issue number5
DOIs
Publication statusPublished - 2002

Keywords

  • Antiphospholipid antibodies
  • Behçet's disease
  • Clinical symptom

ASJC Scopus subject areas

  • Rheumatology

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