TY - JOUR
T1 - Clinical characteristics, management, and outcomes of acute heart failure patients
T2 - Observations from the Gulf acute heart failure registry (Gulf CARE)
AU - Sulaiman, Kadhim
AU - Panduranga, Prashanth
AU - Al-Zakwani, Ibrahim
AU - Alsheikh-Ali, Alawi A.
AU - Alhabib, Khalid F.
AU - Al-Suwaidi, Jassim
AU - Al-Mahmeed, Wael
AU - Alfaleh, Hussam
AU - Elasfar, Abdelfatah
AU - Al-Motarreb, Ahmed
AU - Ridha, Mustafa
AU - Bulbanat, Bassam
AU - Al-Jarallah, Mohammed
AU - Bazargani, Nooshin
AU - Asaad, Nidal
AU - Amin, Haitham
N1 - Publisher Copyright:
© 2015 The Authors. European Journal of Heart Failure © 2015 European Society of Cardiology.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Aims The purpose of this study was to describe the clinical characteristics, management, and outcomes of acute heart failure (HF) patients from the Gulf acute heart failure registry (Gulf CARE). Methods and results Data from 5005 HF patients admitted to 47 hospitals in seven Gulf countries during February to November 2012 were analysed. Fifty-five per cent of patients presented with acute decompensated chronic HF, while 45% had new-onset HF. Mean age was 59±15 years, 63% were males, and 83% were Gulf citizens. Co-morbid conditions were hypertension (61%), diabetes mellitus (50%), CAD (47%), and atrial fibrillation or flutter (14%). The median LVEF was 35% (25-45%) with 69% presenting as HF with reduced EF (HFrEF). CAD was the most prevalent aetiology (53%) followed by idiopathic cardiomyopathy (18%), hypertensive heart disease (16%), and valvular heart disease (9%). At discharge, 71% and 78% of patients received beta-blockers and ACE inhibitors/ARBs, respectively. Use of coronary intervention and device therapy was <10%. In-hospital mortality was 6.3%. Re-hospitalization and cumulative mortality at 3 and 12 months were 18%/13% and 40%/20%, respectively. Conclusions Gulf CARE results show that patients from this region are a decade younger than their Western counterparts, with a high prevalence of diabetes and HFrEF, and a lower prevalence of AF. Use of coronary intervention and device therapy was low, with high re-hospitalization rates. Short- and long-term mortality rates were similar to those of Western registries, but should be interpreted in the light of the younger age of Gulf CARE patients.
AB - Aims The purpose of this study was to describe the clinical characteristics, management, and outcomes of acute heart failure (HF) patients from the Gulf acute heart failure registry (Gulf CARE). Methods and results Data from 5005 HF patients admitted to 47 hospitals in seven Gulf countries during February to November 2012 were analysed. Fifty-five per cent of patients presented with acute decompensated chronic HF, while 45% had new-onset HF. Mean age was 59±15 years, 63% were males, and 83% were Gulf citizens. Co-morbid conditions were hypertension (61%), diabetes mellitus (50%), CAD (47%), and atrial fibrillation or flutter (14%). The median LVEF was 35% (25-45%) with 69% presenting as HF with reduced EF (HFrEF). CAD was the most prevalent aetiology (53%) followed by idiopathic cardiomyopathy (18%), hypertensive heart disease (16%), and valvular heart disease (9%). At discharge, 71% and 78% of patients received beta-blockers and ACE inhibitors/ARBs, respectively. Use of coronary intervention and device therapy was <10%. In-hospital mortality was 6.3%. Re-hospitalization and cumulative mortality at 3 and 12 months were 18%/13% and 40%/20%, respectively. Conclusions Gulf CARE results show that patients from this region are a decade younger than their Western counterparts, with a high prevalence of diabetes and HFrEF, and a lower prevalence of AF. Use of coronary intervention and device therapy was low, with high re-hospitalization rates. Short- and long-term mortality rates were similar to those of Western registries, but should be interpreted in the light of the younger age of Gulf CARE patients.
KW - Acute heart failure
KW - Heart failure
KW - Middle East
KW - Registry
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U2 - 10.1002/ejhf.245
DO - 10.1002/ejhf.245
M3 - Article
C2 - 25739882
AN - SCOPUS:84926203326
SN - 1388-9842
VL - 17
SP - 374
EP - 384
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
IS - 4
ER -