Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Mohamed Arafah; Ali T. Al-Hinai; Wael Al Mahmeed; Khalid Al-Rasadi; Omer Al Tamimi; Shorook Al Herz; Faisal Al Anazi; Khalid Al Nemer; Othman Metwally; Akram Alkhadra; Mohammed Fakhry; Hossam Elghetany; Abdel Razak Medani; Afzal Hussein Yusufali; Obaid Al Jassim; Omar Al Hallaq; Fahad Omar Ahmed S. Baslaib; Mahmoud Alawadhi; Haitham Amin; Khamis Al-Hashmi; Abdullah Shehab

doi:10.1177/0003319713512414

Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Mohamed Arafah, Ali T. Al-Hinai, Wael Al Mahmeed, Khalid Al-Rasadi, Omer Al Tamimi, Shorook Al Herz, Faisal Al Anazi, Khalid Al Nemer, Othman Metwally, Akram Alkhadra, Mohammed Fakhry, Hossam Elghetany, Abdel Razak Medani, Afzal Hussein Yusufali, Obaid Al Jassim, Omar Al Hallaq, Fahad Omar Ahmed S. Baslaib, Mahmoud Alawadhi, Haitham Amin, Khamis Al-HashmiAbdullah Shehab^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

32 Citations (Scopus)

Abstract

The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.

Original language	English
Pages (from-to)	919-926
Number of pages	8
Journal	Angiology
Volume	65
Issue number	10
DOIs	https://doi.org/10.1177/0003319713512414
Publication status	Published - Nov 12 2014

Keywords

Arabian Gulf countries
cardiovascular
coronary
guidelines
hypercholesterolemia
lipids
low-density lipoprotein

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/0003319713512414

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Arafah, M., Al-Hinai, A. T., Mahmeed, W. A., Al-Rasadi, K., Tamimi, O. A., Herz, S. A., Anazi, F. A., Nemer, K. A., Metwally, O., Alkhadra, A., Fakhry, M., Elghetany, H., Medani, A. R., Yusufali, A. H., Jassim, O. A., Hallaq, O. A., Baslaib, F. O. A. S., Alawadhi, M., Amin, H., ... Shehab, A. (2014). Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries. Angiology, 65(10), 919-926. https://doi.org/10.1177/0003319713512414

Arafah, M, Al-Hinai, AT, Mahmeed, WA, Al-Rasadi, K, Tamimi, OA, Herz, SA, Anazi, FA, Nemer, KA, Metwally, O, Alkhadra, A, Fakhry, M, Elghetany, H, Medani, AR, Yusufali, AH, Jassim, OA, Hallaq, OA, Baslaib, FOAS, Alawadhi, M, Amin, H, Al-Hashmi, K & Shehab, A 2014, 'Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries', Angiology, vol. 65, no. 10, pp. 919-926. https://doi.org/10.1177/0003319713512414

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title = "Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries",

abstract = "The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged ≥18 years on LLDs for at least ≥3 months (stable medication for ≥6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age <40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.",

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doi = "10.1177/0003319713512414",

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AU - Arafah, Mohamed

AU - Al-Hinai, Ali T.

AU - Mahmeed, Wael Al

AU - Al-Rasadi, Khalid

AU - Tamimi, Omer Al

AU - Herz, Shorook Al

AU - Anazi, Faisal Al

AU - Nemer, Khalid Al

AU - Metwally, Othman

AU - Alkhadra, Akram

AU - Fakhry, Mohammed

AU - Elghetany, Hossam

AU - Medani, Abdel Razak

AU - Yusufali, Afzal Hussein

AU - Jassim, Obaid Al

AU - Hallaq, Omar Al

AU - Baslaib, Fahad Omar Ahmed S.

AU - Alawadhi, Mahmoud

AU - Amin, Haitham

AU - Al-Hashmi, Khamis

AU - Shehab, Abdullah

PY - 2014/11/12

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Centralized pan-middle east survey on the undertreatment of hypercholesterolemia: Results from the cepheus study in arabian gulf countries

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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