Brain blood flow abnormalities associated with oral cocaine use

Bankole Johnson; Lamk Lamki; Bruce Barron; Ralph Spiga; Richard Chen; Richard Meisch; Neera Khilnani

doi:10.1017/S0790966700003062

Brain blood flow abnormalities associated with oral cocaine use

Bankole Johnson^*, Lamk Lamki, Bruce Barron, Ralph Spiga, Richard Chen, Richard Meisch, Neera Khilnani

^*Corresponding author for this work

Radiology & Molecular Imaging

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Single photon emission tomography (SPECT) is the prototypical tool for measuring cerebral blood flow (CBF) in discrete areas of the brain. Compared with when a male 'crack' cocaine user received placebo, oral cocaine (1 mg/kg) ingestion was associated with non-uniformity of overall CBF with hypoperfusion of discrete brain regions, particularly of the frontal, temporo-parietal, basal ganglia, and thalamic areas. While these results should be viewed as preliminary, they do suggest that oral cocaine use may be associated with CBF abnormalities in 'crack' users.

Original language	English
Pages (from-to)	72-73
Number of pages	2
Journal	Irish Journal of Psychological Medicine
Volume	14
Issue number	2
DOIs	https://doi.org/10.1017/S0790966700003062
Publication status	Published - 1997

Keywords

Brain
Cerebral blood flow
Neuroimaging
Oral cocaine
SPECT
Tc-HMPAO

ASJC Scopus subject areas

Applied Psychology
Psychiatry and Mental health
History and Philosophy of Science

Access to Document

10.1017/S0790966700003062

Cite this

@article{a92fa6d8c8804e9da9b1cda13d1cc845,

title = "Brain blood flow abnormalities associated with oral cocaine use",

abstract = "Single photon emission tomography (SPECT) is the prototypical tool for measuring cerebral blood flow (CBF) in discrete areas of the brain. Compared with when a male 'crack' cocaine user received placebo, oral cocaine (1 mg/kg) ingestion was associated with non-uniformity of overall CBF with hypoperfusion of discrete brain regions, particularly of the frontal, temporo-parietal, basal ganglia, and thalamic areas. While these results should be viewed as preliminary, they do suggest that oral cocaine use may be associated with CBF abnormalities in 'crack' users.",

keywords = "Brain, Cerebral blood flow, Neuroimaging, Oral cocaine, SPECT, Tc-HMPAO",

author = "Bankole Johnson and Lamk Lamki and Bruce Barron and Ralph Spiga and Richard Chen and Richard Meisch and Neera Khilnani",

year = "1997",

doi = "10.1017/S0790966700003062",

language = "English",

volume = "14",

pages = "72--73",

journal = "Irish Journal of Psychological Medicine",

issn = "0790-9667",

publisher = "MedMedia Ltd",

number = "2",

}

TY - JOUR

T1 - Brain blood flow abnormalities associated with oral cocaine use

AU - Johnson, Bankole

AU - Lamki, Lamk

AU - Barron, Bruce

AU - Spiga, Ralph

AU - Chen, Richard

AU - Meisch, Richard

AU - Khilnani, Neera

PY - 1997

Y1 - 1997

N2 - Single photon emission tomography (SPECT) is the prototypical tool for measuring cerebral blood flow (CBF) in discrete areas of the brain. Compared with when a male 'crack' cocaine user received placebo, oral cocaine (1 mg/kg) ingestion was associated with non-uniformity of overall CBF with hypoperfusion of discrete brain regions, particularly of the frontal, temporo-parietal, basal ganglia, and thalamic areas. While these results should be viewed as preliminary, they do suggest that oral cocaine use may be associated with CBF abnormalities in 'crack' users.

AB - Single photon emission tomography (SPECT) is the prototypical tool for measuring cerebral blood flow (CBF) in discrete areas of the brain. Compared with when a male 'crack' cocaine user received placebo, oral cocaine (1 mg/kg) ingestion was associated with non-uniformity of overall CBF with hypoperfusion of discrete brain regions, particularly of the frontal, temporo-parietal, basal ganglia, and thalamic areas. While these results should be viewed as preliminary, they do suggest that oral cocaine use may be associated with CBF abnormalities in 'crack' users.

KW - Brain

KW - Cerebral blood flow

KW - Neuroimaging

KW - Oral cocaine

KW - SPECT

KW - Tc-HMPAO

UR - http://www.scopus.com/inward/record.url?scp=0030852254&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030852254&partnerID=8YFLogxK

U2 - 10.1017/S0790966700003062

DO - 10.1017/S0790966700003062

M3 - Article

AN - SCOPUS:0030852254

SN - 0790-9667

VL - 14

SP - 72

EP - 73

JO - Irish Journal of Psychological Medicine

JF - Irish Journal of Psychological Medicine

IS - 2

ER -

Brain blood flow abnormalities associated with oral cocaine use

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this