Biological activities of Boswellia sacra extracts on the growth and aflatoxins secretion of two aflatoxigenic species of Aspergillus species

Saifeldin A F El-Nagerabi, Abdulkadir E. Elshafie, Suleiman S. AlKhanjari, Saif N. Al-Bahry, Mohamed R. Elamin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Aflatoxins are the most serious carcinogenic, hepatotoxic, teratogenic and mutagenic secondary metabolites which adversely affect human and animal health. This study was designed to evaluate the invitro inhibitory effect of different concentrations of Boswellia sacra resin (2.5, 5, 7.5 and 10g/100ml), leaf extract (5, 7.5, 10, 12.5 and 15ml/100ml), and essential oil (1, 2, 3, and 4ml/100ml) on the growth and aflatoxins production by two species of Aspergilli, namely Aspergillus flavus (SQU21) and Aspergillus parasiticus (CBS921.7). Resin of B.sacra caused 57.9-92.1% inhibition of aflatoxin secretion by A.flavus and 43.6-95.7% for A.parasiticus. However, the mycelial dry weights were significantly increased by 20.9-52.7% for A.flavus, and 8.9-68.5% for A.parasiticus. The leaf extract of B.sacra apparently enhanced aflatoxins production by 20-50%, and mycelial dry weight by 25.5-29.1% for A.flavus and A.parasiticus. The essential oil of B.sacra at different concentrations similarly inhibited the fungal growth and aflatoxins production by 45.8-83.7% for A.flavus and 41.3-83.5% for A.parasiticus which indicates the antifungal activity of this oil. None of the B.sacra extracts detoxified pure aqueous aflatoxin B1. We have concluded that B.sacra resin and essential oil possess biological activity against biochemical synthesis and metabolic pathway of aflatoxin production of the two Aspergillus species. Therefore, the resin and essential oil of B.sacra can be recommended as safe plant based bioreservatives to enhance shelf life of food and feed products with reference to adverse effect of physical and synthetic chemical preservatives and their antimicrobial and aflatoxins inhibition activity.

Original languageEnglish
Pages (from-to)763-769
Number of pages7
JournalFood Control
Volume34
Issue number2
DOIs
Publication statusPublished - Dec 2013

Fingerprint

Boswellia
Aflatoxins
Sacrum
Aspergillus
aflatoxins
bioactive properties
secretion
Volatile Oils
extracts
Growth
resins
essential oils
leaf extracts
Food Storage
Weights and Measures
Aspergillus flavus
Aspergillus parasiticus
Aflatoxin B1
animal and human health
aflatoxin B1

Keywords

  • A.parasiticus
  • Aflatoxins
  • Aspergillus flavus
  • Detoxification
  • Frankincense

ASJC Scopus subject areas

  • Food Science
  • Biotechnology

Cite this

Biological activities of Boswellia sacra extracts on the growth and aflatoxins secretion of two aflatoxigenic species of Aspergillus species. / El-Nagerabi, Saifeldin A F; Elshafie, Abdulkadir E.; AlKhanjari, Suleiman S.; Al-Bahry, Saif N.; Elamin, Mohamed R.

In: Food Control, Vol. 34, No. 2, 12.2013, p. 763-769.

Research output: Contribution to journalArticle

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abstract = "Aflatoxins are the most serious carcinogenic, hepatotoxic, teratogenic and mutagenic secondary metabolites which adversely affect human and animal health. This study was designed to evaluate the invitro inhibitory effect of different concentrations of Boswellia sacra resin (2.5, 5, 7.5 and 10g/100ml), leaf extract (5, 7.5, 10, 12.5 and 15ml/100ml), and essential oil (1, 2, 3, and 4ml/100ml) on the growth and aflatoxins production by two species of Aspergilli, namely Aspergillus flavus (SQU21) and Aspergillus parasiticus (CBS921.7). Resin of B.sacra caused 57.9-92.1{\%} inhibition of aflatoxin secretion by A.flavus and 43.6-95.7{\%} for A.parasiticus. However, the mycelial dry weights were significantly increased by 20.9-52.7{\%} for A.flavus, and 8.9-68.5{\%} for A.parasiticus. The leaf extract of B.sacra apparently enhanced aflatoxins production by 20-50{\%}, and mycelial dry weight by 25.5-29.1{\%} for A.flavus and A.parasiticus. The essential oil of B.sacra at different concentrations similarly inhibited the fungal growth and aflatoxins production by 45.8-83.7{\%} for A.flavus and 41.3-83.5{\%} for A.parasiticus which indicates the antifungal activity of this oil. None of the B.sacra extracts detoxified pure aqueous aflatoxin B1. We have concluded that B.sacra resin and essential oil possess biological activity against biochemical synthesis and metabolic pathway of aflatoxin production of the two Aspergillus species. Therefore, the resin and essential oil of B.sacra can be recommended as safe plant based bioreservatives to enhance shelf life of food and feed products with reference to adverse effect of physical and synthetic chemical preservatives and their antimicrobial and aflatoxins inhibition activity.",
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AU - Elamin, Mohamed R.

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N2 - Aflatoxins are the most serious carcinogenic, hepatotoxic, teratogenic and mutagenic secondary metabolites which adversely affect human and animal health. This study was designed to evaluate the invitro inhibitory effect of different concentrations of Boswellia sacra resin (2.5, 5, 7.5 and 10g/100ml), leaf extract (5, 7.5, 10, 12.5 and 15ml/100ml), and essential oil (1, 2, 3, and 4ml/100ml) on the growth and aflatoxins production by two species of Aspergilli, namely Aspergillus flavus (SQU21) and Aspergillus parasiticus (CBS921.7). Resin of B.sacra caused 57.9-92.1% inhibition of aflatoxin secretion by A.flavus and 43.6-95.7% for A.parasiticus. However, the mycelial dry weights were significantly increased by 20.9-52.7% for A.flavus, and 8.9-68.5% for A.parasiticus. The leaf extract of B.sacra apparently enhanced aflatoxins production by 20-50%, and mycelial dry weight by 25.5-29.1% for A.flavus and A.parasiticus. The essential oil of B.sacra at different concentrations similarly inhibited the fungal growth and aflatoxins production by 45.8-83.7% for A.flavus and 41.3-83.5% for A.parasiticus which indicates the antifungal activity of this oil. None of the B.sacra extracts detoxified pure aqueous aflatoxin B1. We have concluded that B.sacra resin and essential oil possess biological activity against biochemical synthesis and metabolic pathway of aflatoxin production of the two Aspergillus species. Therefore, the resin and essential oil of B.sacra can be recommended as safe plant based bioreservatives to enhance shelf life of food and feed products with reference to adverse effect of physical and synthetic chemical preservatives and their antimicrobial and aflatoxins inhibition activity.

AB - Aflatoxins are the most serious carcinogenic, hepatotoxic, teratogenic and mutagenic secondary metabolites which adversely affect human and animal health. This study was designed to evaluate the invitro inhibitory effect of different concentrations of Boswellia sacra resin (2.5, 5, 7.5 and 10g/100ml), leaf extract (5, 7.5, 10, 12.5 and 15ml/100ml), and essential oil (1, 2, 3, and 4ml/100ml) on the growth and aflatoxins production by two species of Aspergilli, namely Aspergillus flavus (SQU21) and Aspergillus parasiticus (CBS921.7). Resin of B.sacra caused 57.9-92.1% inhibition of aflatoxin secretion by A.flavus and 43.6-95.7% for A.parasiticus. However, the mycelial dry weights were significantly increased by 20.9-52.7% for A.flavus, and 8.9-68.5% for A.parasiticus. The leaf extract of B.sacra apparently enhanced aflatoxins production by 20-50%, and mycelial dry weight by 25.5-29.1% for A.flavus and A.parasiticus. The essential oil of B.sacra at different concentrations similarly inhibited the fungal growth and aflatoxins production by 45.8-83.7% for A.flavus and 41.3-83.5% for A.parasiticus which indicates the antifungal activity of this oil. None of the B.sacra extracts detoxified pure aqueous aflatoxin B1. We have concluded that B.sacra resin and essential oil possess biological activity against biochemical synthesis and metabolic pathway of aflatoxin production of the two Aspergillus species. Therefore, the resin and essential oil of B.sacra can be recommended as safe plant based bioreservatives to enhance shelf life of food and feed products with reference to adverse effect of physical and synthetic chemical preservatives and their antimicrobial and aflatoxins inhibition activity.

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