Bacille Calmette-Guérin vaccine-induced tuberculous hip osteomyelitis in an infant: Case report

Mohammed S. Al-Azri, Jazel Manarang, Yaqoub Al-Mufargi

Research output: Contribution to journalArticle

Abstract

To this day, tuberculosis (TB) continues to pose a significant global health burden. The World Health Organization’s Expanded Programme on Immunization (EPI) recommends the bacille Calmette-Guérin (BCG) vaccine for infants to protect against the haematogenous spread of primary TB and other more severe types of TB infection. We report an eight-month-old boy who presented to the Armed Forces Hospital, Muscat, Oman, in 2015 with a one-month history of intermittent fever associated with a limited range of motion in the right hip area. He was up-to-date with his EPI vaccinations and had no history of exposure to individuals with TB infections. He was initially treated for bacterial septic arthritis; however, a GeneXpert TB assay revealed the presence of Mycobacterium tuberculosis, BCG strain. To the best of the authors’ knowledge, this is the first documented case from Oman of a child with TB hip osteomyelitis due to a BCG vaccination.

Original languageEnglish
Pages (from-to)e358-e362
JournalSultan Qaboos University Medical Journal
Volume17
Issue number3
DOIs
Publication statusPublished - Aug 1 2017

Keywords

  • Adverse effects
  • BCG vaccine
  • Case report
  • Oman
  • Osteomyelitis
  • Tuberculosis
  • Vaccination

ASJC Scopus subject areas

  • Medicine(all)

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