Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease

Herbert Weissenböck, Tamás Bakonyi, Karin Sekulin, Felix Ehrensperger, Robert J T Doneley, Ralf Dürrwald, Richard Hoop, Károly Erdélyi, János Gál, Jolanta Kolodziejek, Norbert Nowotny

Research output: Contribution to journalArticle

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Abstract

To determine whether avian bornaviruses (ABVs) were a factor in proventricular dilatation disease (PDD), we used immunohistochemistry, reverse transcription - PCR, and nucleotide sequence analysis to examine paraffin wax - embedded or frozen tissue samples of 31 psittacine birds with this disease. PDD is a fatal disease of psittacine birds associated with nonsuppurative encephalitis and ganglioneuritis of the upper intestinal tract. Tissue samples had been collected from 1999 through 2008 in Austria, Switzerland, Hungary, and Australia. Immunohistochemical demonstration of viral antigen within the brain and vegetative nerve system of the gastrointestinal tract provides strong evidence for a causative role of ABVs in this condition. Partial sequences of nucleoprotein (p40) and matrix protein (gp18) genes showed that virus in most of our cases belonged to the ABV-2 and ABV-4 groups among the 5 genogroups described so far. Viral sequences of 2 birds did not match any of the described sequences and clustered together in a new branch termed ABV-6.

Original languageEnglish
Pages (from-to)1453-1459
Number of pages7
JournalEmerging Infectious Diseases
Volume15
Issue number9
DOIs
Publication statusPublished - Sep 2009

Fingerprint

Bornaviridae
Psittaciformes
Birds
Dilatation
Bird Diseases
Austria-Hungary
Nucleoproteins
Viral Antigens
Waxes
Encephalitis
Switzerland
Paraffin
Reverse Transcription
Sequence Analysis
Gastrointestinal Tract
Immunohistochemistry
Genotype
Viruses
Polymerase Chain Reaction
Brain

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

Weissenböck, H., Bakonyi, T., Sekulin, K., Ehrensperger, F., Doneley, R. J. T., Dürrwald, R., ... Nowotny, N. (2009). Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. Emerging Infectious Diseases, 15(9), 1453-1459. https://doi.org/10.3201/eid1509.090353

Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. / Weissenböck, Herbert; Bakonyi, Tamás; Sekulin, Karin; Ehrensperger, Felix; Doneley, Robert J T; Dürrwald, Ralf; Hoop, Richard; Erdélyi, Károly; Gál, János; Kolodziejek, Jolanta; Nowotny, Norbert.

In: Emerging Infectious Diseases, Vol. 15, No. 9, 09.2009, p. 1453-1459.

Research output: Contribution to journalArticle

Weissenböck, H, Bakonyi, T, Sekulin, K, Ehrensperger, F, Doneley, RJT, Dürrwald, R, Hoop, R, Erdélyi, K, Gál, J, Kolodziejek, J & Nowotny, N 2009, 'Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease', Emerging Infectious Diseases, vol. 15, no. 9, pp. 1453-1459. https://doi.org/10.3201/eid1509.090353
Weissenböck H, Bakonyi T, Sekulin K, Ehrensperger F, Doneley RJT, Dürrwald R et al. Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. Emerging Infectious Diseases. 2009 Sep;15(9):1453-1459. https://doi.org/10.3201/eid1509.090353
Weissenböck, Herbert ; Bakonyi, Tamás ; Sekulin, Karin ; Ehrensperger, Felix ; Doneley, Robert J T ; Dürrwald, Ralf ; Hoop, Richard ; Erdélyi, Károly ; Gál, János ; Kolodziejek, Jolanta ; Nowotny, Norbert. / Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease. In: Emerging Infectious Diseases. 2009 ; Vol. 15, No. 9. pp. 1453-1459.
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