Association between dietary and lifestyle indices and colorectal cancer in Oman: A Case-control study

Rose N. Mafiana, Ahmed S. Al Lawati, Mostafa Waly, Yahya Al-Farsi, Maimouna Al Kindi, Mansour Al Moundhri

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Colorectal cancer (CRC) represents a heterogeneous group of diseases characterized by uncontrolled growth and spread of abnormal cells in the body. CRC vary on the basis of both the biologic features of the disease and its associated lifestyle characteristics. The risk of CRC increases with several modifiable factors including obesity, physical inactivity, a diet high in red or processed meat, heavy alcohol consumption, and possibly inadequate intake of fruits and vegetables. We aimed to establish a baseline data for dietary and lifestyle characteristics of Omani adults diagnosed with CRC. Methods: A Case control study conducted at Sultan Qaboos University Hospital, a referral hospital for CRC patients in Oman, and included 279 subjects (109 diagnosed CRC cases and 170 matched controls). All study subjects were recruited on volunteer basis and personally interviewed for preset questions related to sociodemographic data, anthropometric assessment, dietary intake and physical activity. Results: There was no significant difference between cases and controls regarding smoking, alcohol intake, physical activity and dietary fiber intake. However the enrolled cases were more overweight (OR =3.27. 95% CI: 1.91, 7.27), and, had a higher caloric (p =0.001) and macronutrient intake (carbohydrate: p = 0.001; protein: p = 0.017; saturated fat: P = 0.034) than the controls. In addition, the dietary pattern of the cases was characterized by a trend towards low vegetables and fruits intake. Conclusion: CRC maybe prevented through dietary management of high risk groups. This primary prevention approach will ultimately reduce the burden of CRC in Oman.

Original languageEnglish
Pages (from-to)3117-3122
Number of pages6
JournalAsian Pacific Journal of Cancer Prevention
Volume19
Issue number11
DOIs
Publication statusPublished - Jan 1 2018

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Oman
Case-Control Studies
Life Style
Colorectal Neoplasms
Vegetables
Fruit
Exercise
Risk Management
Dietary Fiber
Primary Prevention
Alcohol Drinking
Meat
Volunteers
Referral and Consultation
Obesity
Smoking
Fats
Alcohols
Carbohydrates
Diet

Keywords

  • Colorectal cancer
  • Diet
  • Lifestyle
  • Oman

ASJC Scopus subject areas

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research

Cite this

Association between dietary and lifestyle indices and colorectal cancer in Oman : A Case-control study. / Mafiana, Rose N.; Al Lawati, Ahmed S.; Waly, Mostafa; Al-Farsi, Yahya; Al Kindi, Maimouna; Al Moundhri, Mansour.

In: Asian Pacific Journal of Cancer Prevention, Vol. 19, No. 11, 01.01.2018, p. 3117-3122.

Research output: Contribution to journalArticle

Mafiana, Rose N. ; Al Lawati, Ahmed S. ; Waly, Mostafa ; Al-Farsi, Yahya ; Al Kindi, Maimouna ; Al Moundhri, Mansour. / Association between dietary and lifestyle indices and colorectal cancer in Oman : A Case-control study. In: Asian Pacific Journal of Cancer Prevention. 2018 ; Vol. 19, No. 11. pp. 3117-3122.
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