Antimicrobial activity of Acacia nilotica subspp. nilotica fruit extracts

N. K. Mustafa*, M. O M Tanira, F. K. Dar, H. Nsanze

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.

Original languageEnglish
Pages (from-to)583-586
Number of pages4
JournalPharmacy and Pharmacology Communications
Volume5
Issue number9
Publication statusPublished - Sep 1999

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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