Abstract
The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
Original language | English |
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Pages (from-to) | 583-586 |
Number of pages | 4 |
Journal | Pharmacy and Pharmacology Communications |
Volume | 5 |
Issue number | 9 |
Publication status | Published - Sep 1999 |
ASJC Scopus subject areas
- Pharmacology
- Pharmaceutical Science