TY - JOUR
T1 - Antimicrobial activity of Acacia nilotica subspp. nilotica fruit extracts
AU - Mustafa, N. K.
AU - Tanira, M. O.M.
AU - Dar, F. K.
AU - Nsanze, H.
PY - 1999/9
Y1 - 1999/9
N2 - The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
AB - The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
UR - http://www.scopus.com/inward/record.url?scp=0032827006&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032827006&partnerID=8YFLogxK
U2 - 10.1211/146080899128735306
DO - 10.1211/146080899128735306
M3 - Article
AN - SCOPUS:0032827006
SN - 0022-3573
VL - 5
SP - 583
EP - 586
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
IS - 9
ER -