Abstract
The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
| Original language | English |
|---|---|
| Pages (from-to) | 583-586 |
| Number of pages | 4 |
| Journal | Pharmacy and Pharmacology Communications |
| Volume | 5 |
| Issue number | 9 |
| Publication status | Published - Sep 1999 |
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ASJC Scopus subject areas
- Pharmacology
- Pharmaceutical Science
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Antimicrobial activity of Acacia nilotica subspp. nilotica fruit extracts. / Mustafa, N. K.; Tanira, M. O M; Dar, F. K.; Nsanze, H.
In: Pharmacy and Pharmacology Communications, Vol. 5, No. 9, 09.1999, p. 583-586.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antimicrobial activity of Acacia nilotica subspp. nilotica fruit extracts
AU - Mustafa, N. K.
AU - Tanira, M. O M
AU - Dar, F. K.
AU - Nsanze, H.
PY - 1999/9
Y1 - 1999/9
N2 - The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
AB - The fruit of Acacia nilotica subspp. nilotica is a traditional medicinal remedy, widely used in the Sudan and other Arab countries. Water, ethanol, n-hexane and chloroform extracts were prepared from dried powdered fruit and tested for in-vitro antimicrobial activity against human pathogenic bacteria and Candida albicans, using agar dilution and broth microdilution methods. The extracts had a varying degree of antimicrobial activity. Extracts in water and ethanol were generally more active than those in n-hexane and chloroform. The extracts were more effective against Gram positive cocci than Gram-negative bacilli. Antifungal activity against Candida albicans was found in the n-hexane extract only. The results indicate the therapeutic value of A. nilotica extracts as potential antimicrobial agents.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032827006&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0032827006
VL - 5
SP - 583
EP - 586
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
SN - 0022-3573
IS - 9
ER -