Anesthetic molecule interaction of noble gases with proteins and lipids and their effect: A review

Shyamal Kumar Kundu*, Chiranjib Chakraborty, Shin Yagihara, Seong Lin Teoh, Srijit Das

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Surgical operations are impossible without administering proper analgesia. Advancement in the field of anesthesia has invariably resulted in the accomplishment of all surgical processes without any inconvenience. Admittedly, the use of noble gas is on the decline. The noble gases may not interact chemically with any other substance under normal temperature and pressure but they may interact with proteins and lipids. Different anesthetic molecules may stimulate either proteins or lipids in membrane. There is a connection between the anesthetic molecules and the hydrophobic region of the membrane. In the present review, we attempt to highlight the interaction between the anesthetic molecule with proteins and lipids and their effects. We sketched few noble gases and some other existing molecules such as halothane and alcohol which interacted with proteins and lipids.

Original languageEnglish
Pages (from-to)1381-1392
Number of pages12
JournalCurrent Drug Delivery
Volume15
Issue number10
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • Anesthesia
  • Effect
  • Interactions
  • Lipids
  • Membrane
  • Protein

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this