Abstract
Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.
| Original language | English |
|---|---|
| Pages (from-to) | 467-471 |
| Number of pages | 5 |
| Journal | Sultan Qaboos University Medical Journal |
| Volume | 13 |
| Issue number | 3 |
| Publication status | Published - Aug 2013 |
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Keywords
- Anesthesia
- C1 esterase inhibitor deficiency
- Case report
- Hereditary angioedema
- Oman
ASJC Scopus subject areas
- Medicine(all)
Cite this
Anaesthesia management of a patient with hereditary angioedema with prophylactic administration of C1 esterase inhibitor : Case report and literature review. / Narayanan, Aravind; Date, Rohit R.; Birur, Sanathkumar; Bhakta, Pradipta; Srinivasan, Sinnakirouchenane.
In: Sultan Qaboos University Medical Journal, Vol. 13, No. 3, 08.2013, p. 467-471.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anaesthesia management of a patient with hereditary angioedema with prophylactic administration of C1 esterase inhibitor
T2 - Case report and literature review
AU - Narayanan, Aravind
AU - Date, Rohit R.
AU - Birur, Sanathkumar
AU - Bhakta, Pradipta
AU - Srinivasan, Sinnakirouchenane
PY - 2013/8
Y1 - 2013/8
N2 - Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.
AB - Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.
KW - Anesthesia
KW - C1 esterase inhibitor deficiency
KW - Case report
KW - Hereditary angioedema
KW - Oman
UR - http://www.scopus.com/inward/record.url?scp=84880960952&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880960952&partnerID=8YFLogxK
M3 - Article
VL - 13
SP - 467
EP - 471
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
SN - 2075-051X
IS - 3
ER -