An efficient one-pot synthesis of pyrazolopyrimidines, intermediates for potential phosphodiesterase inhibitors

Raid J. Abdel-Jalil, Monther Khanfar, Kayed Abu-Safieh, Samer Al-Gharabli, Mustafa El-Abadelah, Wolfgang Voelter

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A simple high-yielding procedure is presented for the synthesis of pyrazolopyrimidinones overcoming limitations found in earlier work and of considerable utility for the production of intermediates for potential phosphodiesterase inhibitors.

Original languageEnglish
Pages (from-to)619-624
Number of pages6
JournalMonatshefte fur Chemie
Volume136
Issue number4
DOIs
Publication statusPublished - Apr 2005

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Keywords

  • Phosphodiesterase inhibitors
  • Pyrazolopyrimidones
  • Viagra®

ASJC Scopus subject areas

  • Chemistry(all)

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