Amlodipine: The double edged sword

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Aim: Amlodipine, a calcium channel blocker became one of the most popular antihypertensive medications used in the paediatric population. This is mainly due to its long half-life making it easy to use as a single daily dose. Amlodipine is associated with common side effects like flushing, headache and dizziness. The incidence of amlodipine-related oedema was noted to be lower in the paediatric population compared to adults. We emphasise the importance of monitoring the development of oedema in patients treated with amlodipine. Methods: Hereby, we report four paediatric cases with amlodipine-related generalised oedema. Conclusion: Resolution of the oedema with stoppage of amlodipine confirms its culprit as a cause of the oedema. To our knowledge, this is the largest case series of amlodipine-related generalised oedema in the paediatric population.

Original languageEnglish
JournalJournal of Paediatrics and Child Health
DOIs
Publication statusAccepted/In press - 2017

Fingerprint

Amlodipine
Edema
Pediatrics
Population
Calcium Channel Blockers
Dizziness
Antihypertensive Agents
Headache
Half-Life
Incidence

Keywords

  • Amlodipine
  • Oedema
  • Paediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Amlodipine : The double edged sword. / Rabah, Fatma; El-Naggari, Mohamed; Al-Nabhani, Dana.

In: Journal of Paediatrics and Child Health, 2017.

Research output: Contribution to journalArticle

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