TY - JOUR
T1 - Advanced fabrication for electrospun three-dimensional nanofiber aerogels and scaffolds
AU - Chen, Yujie
AU - Shafiq, Muhammad
AU - Liu, Mingyue
AU - Morsi, Yosry
AU - Mo, Xiumei
N1 - Funding Information:
This research was supported by the Fundamental Research Funds for the Central Universities (Grant No. 2232019A3-07 ), National Key Research Program of China ( 2016YFC1100202 ); National Natural Science Foundation of China (No. 31771023 ); Science and Technology Commission of Shanghai Municipality (No. 19441902600 ), and a startup research grant of Higher Education Commission (HEC), Pakistan (Project No. 2089 ).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Electrospinning is a versatile strategy for creating nanofiber materials with various structures, which has broad application for a myriad of areas ranging from tissue engineering, energy harvesting, filtration and has become one of the most important academic and technical activities in the field of material science in recent years. In addition to playing a significant role in the construction of two-dimensional (2D) nanomaterials, electrospinning holds great promise as a robust method for producing three-dimensional (3D) aerogels and scaffolds. This article reviews and summarizes the recent advanced methods for fabricating electrospun three-dimensional nanofiber aerogels and scaffolds, including gas foaming, direct electrospinning of 3D nanofibrous scaffold, short nanofibers assembling into 3D aerogels/scaffolds, 3D printing, electrospray, origami and cell sheet engineering, centrifugal electrospinning, and other methods. Besides, intriguing formation process, crosslinking pathway, properties, and applications of 3D aerogels and scaffolds are also introduced. Taken together, these aerogels and scaffolds with various excellent features present tremendous potential in various fields.
AB - Electrospinning is a versatile strategy for creating nanofiber materials with various structures, which has broad application for a myriad of areas ranging from tissue engineering, energy harvesting, filtration and has become one of the most important academic and technical activities in the field of material science in recent years. In addition to playing a significant role in the construction of two-dimensional (2D) nanomaterials, electrospinning holds great promise as a robust method for producing three-dimensional (3D) aerogels and scaffolds. This article reviews and summarizes the recent advanced methods for fabricating electrospun three-dimensional nanofiber aerogels and scaffolds, including gas foaming, direct electrospinning of 3D nanofibrous scaffold, short nanofibers assembling into 3D aerogels/scaffolds, 3D printing, electrospray, origami and cell sheet engineering, centrifugal electrospinning, and other methods. Besides, intriguing formation process, crosslinking pathway, properties, and applications of 3D aerogels and scaffolds are also introduced. Taken together, these aerogels and scaffolds with various excellent features present tremendous potential in various fields.
KW - Aerogels
KW - Electrospun nanofibers
KW - Three-dimensional scaffolds
KW - Tissue engineering
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U2 - 10.1016/j.bioactmat.2020.06.023
DO - 10.1016/j.bioactmat.2020.06.023
M3 - Review article
AN - SCOPUS:85087287099
VL - 5
SP - 963
EP - 979
JO - Bioactive Materials
JF - Bioactive Materials
SN - 2452-199X
IS - 4
ER -