Acute urticaria and hepatitis complicating high‐dose methotrexate therapy

Zakiya Al‐Lamki, Eileen Thomas, Nagwa El‐Banna, Norman Jaffe*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


We report an unusual case of anaphylaxis and hepatitic dysfunction in a child with the administration of the twenty‐third course of high‐dose methotrexate. The latter had been used as an adjuvant to prevent pulmonary metastases and the prior 22 courses had been well tolerated. An attempt to reinstate methotrexate after the twenty‐third course was again followed by a similar reaction. © 1995 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalMedical and Pediatric Oncology
Issue number2
Publication statusPublished - Feb 1995


  • hepatitis
  • high dose methotrexate
  • urticaria

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research


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