TY - JOUR
T1 - Acquired inhibitor to factor VIII
T2 - Report of two unusual cases
AU - Pathare, A. V.
AU - Ghamande, S.
AU - Fernandes, S.
AU - Bhatia, S.
AU - Jijina, F.
AU - Shetty, S.
AU - Ghosh, K.
AU - Mohanty, D.
PY - 1997
Y1 - 1997
N2 - The present report describes two unusual cases of bleeding due to development of inhibitor against factor VIII. One of the patients was known to have severe haemophilia B (factor IX < 1%) and the other, a healthy male of 46 years, spontaneously started to bleed and was found to have developed inhibitors to factor VIII:C along with other autoantibodies. Development of inhibitors to coagulation factors is a serious clinical problem in developed countries and is more so in developing countries where treatment options are often limited.
AB - The present report describes two unusual cases of bleeding due to development of inhibitor against factor VIII. One of the patients was known to have severe haemophilia B (factor IX < 1%) and the other, a healthy male of 46 years, spontaneously started to bleed and was found to have developed inhibitors to factor VIII:C along with other autoantibodies. Development of inhibitors to coagulation factors is a serious clinical problem in developed countries and is more so in developing countries where treatment options are often limited.
KW - Acquired haemophilia
KW - Autoantibodies
KW - Factor VIII inhibitors
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U2 - 10.1046/j.1365-2516.1997.00094.x
DO - 10.1046/j.1365-2516.1997.00094.x
M3 - Article
C2 - 27214809
AN - SCOPUS:0030824425
VL - 3
SP - 212
EP - 214
JO - Haemophilia
JF - Haemophilia
SN - 1351-8216
IS - 3
ER -