Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia: Results from the ESCALATOR study

Ali Taher; Mohsen S. Elalfy; Kusai Al Zir; Shahina Daar; Abdullah Al Jefri; Dany Habr; Ulrike Kriemler-Krahn; Bernard Roubert; Amal El-Beshlawy

doi:10.1111/j.1600-0609.2011.01661.x

Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia: Results from the ESCALATOR study

Ali Taher^*, Mohsen S. Elalfy, Kusai Al Zir, Shahina Daar, Abdullah Al Jefri, Dany Habr, Ulrike Kriemler-Krahn, Bernard Roubert, Amal El-Beshlawy

^*Corresponding author for this work

Haematology

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

This analysis evaluated the effects of deferasirox on liver iron concentration in moderate and heavily iron-overloaded patients with β-thalassaemia from the ESCALATOR trial (n=231). Mean liver iron concentrations (LIC) decreased significantly from 21.1±8.2 to 14.2±12.1mg Fe/g dry weight (dw) at 2yr (P

Original language	English
Pages (from-to)	349-354
Number of pages	6
Journal	European Journal of Haematology
Volume	87
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0609.2011.01661.x
Publication status	Published - Oct 2011

Keywords

β-thalassaemia
Deferasirox
Efficacy
Iron chelation therapy
Iron overload

ASJC Scopus subject areas

Hematology

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Taher, A., Elalfy, M. S., Al Zir, K., Daar, S., Al Jefri, A., Habr, D., Kriemler-Krahn, U., Roubert, B., & El-Beshlawy, A. (2011). Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia: Results from the ESCALATOR study. European Journal of Haematology, 87(4), 349-354. https://doi.org/10.1111/j.1600-0609.2011.01661.x

Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia : Results from the ESCALATOR study. / Taher, Ali; Elalfy, Mohsen S.; Al Zir, Kusai; Daar, Shahina; Al Jefri, Abdullah; Habr, Dany; Kriemler-Krahn, Ulrike; Roubert, Bernard; El-Beshlawy, Amal.

In: European Journal of Haematology, Vol. 87, No. 4, 10.2011, p. 349-354.

Research output: Contribution to journal › Article › peer-review

Taher, A, Elalfy, MS, Al Zir, K, Daar, S, Al Jefri, A, Habr, D, Kriemler-Krahn, U, Roubert, B & El-Beshlawy, A 2011, 'Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia: Results from the ESCALATOR study', European Journal of Haematology, vol. 87, no. 4, pp. 349-354. https://doi.org/10.1111/j.1600-0609.2011.01661.x

Taher, Ali ; Elalfy, Mohsen S. ; Al Zir, Kusai ; Daar, Shahina ; Al Jefri, Abdullah ; Habr, Dany ; Kriemler-Krahn, Ulrike ; Roubert, Bernard ; El-Beshlawy, Amal. / Achieving treatment goals of reducing or maintaining body iron burden with deferasirox in patients with β-thalassaemia : Results from the ESCALATOR study. In: European Journal of Haematology. 2011 ; Vol. 87, No. 4. pp. 349-354.

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