Abstract
Twenty-seven cases of Kala-azar were treated with sodium stibogluconate at a dose of 20 mg/ kg/day for 20 days (group A) and an equal number of cases were treated with the same dose but for a longer duration of 30 days (group B). Clinical and laboratory evaluation of these cases were carried out before and after therapy, during a follow up of cases every month, upto 6 months. Renal and liver function tests and electrocardiography were carried out of monitor any toxic effect of the drug during therapy. The cure rates of patients were 77.78% and 92.59% in group A and B cases respectively. Six and two patients in group A and B respectively were unresponsive to the treatment and showed relapse. Results of the study show that treatment of cases of Kala-azar with sodium stibogluconate in a dosage of 20 mg/kg/day for a longer period of 30 days is effective with a higher cure rate and minimum side effects, for treatment of cases of Kala-azar in this eastern part of Nepal, endemic for the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 154-158 |
| Number of pages | 5 |
| Journal | Southeast Asian Journal of Tropical Medicine and Public Health |
| Volume | 29 |
| Issue number | 1 |
| Publication status | Published - Mar 1998 |
| Externally published | Yes |
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Infectious Diseases
