Abstract
A one pot reaction of the epoxy triflates 1 or 2 with a variety of N',N'-disubstituted ethylenediamines yields the corresponding chiral piperazine derivatives 3a-e and 4a-e of potential pharmacological interest in high yields.
Original language | English |
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Pages (from-to) | 7703-7704 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 39 |
Issue number | 42 |
DOIs | |
Publication status | Published - Oct 15 1998 |
Externally published | Yes |
Keywords
- Anhydro sugars
- Chiral piperazines
- Piperazine derivatives
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry