A solid state sensor based polytyramine film modified electrode for the determination of dopamine and ascorbic acid in a moderately acidic solution

Emad A. Khudaish, Khawla Y. Al-Ajmi, Salim H. Al-Harthi, Ashraf T. Al-Hinai

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A thin film of polytyramine (Pty) was deposited on the surface of a glassy carbon electrode (GCE) in phosphate buffer solution (pH = 4.1) by reversible potentiodynamic scans in the range of -200 mV to +1000 mV. The reactivity of the polymeric film was characterized using electrochemical methods in the presence of redox couple species and scan rate variations. The concentration of the generated polymeric film was 2.91 × 10 -10 mol cm -2 while the amount deposited during the entire repetitive cycles approaches 12.9 μg. The mean surface roughness estimated by Scanning Tunneling Spectroscopy (STM) technique is 0.7 nm, interestingly indicates the formation of a very thin layer. The modified electrode exhibited a substantial reactivity and high sensitivity in the oxidation of dopamine (DA) and ascorbic acid (AA). The symmetry and peak separation for both biological components were identified and the expected interference capacity by either component has been advantageously eliminated to a larger extent. The present working system provides a simple and fundamental approach for the simultaneous and selective determination of DA and AA with a detection limit brought down to 142 nM and 331 nM, respectively.

Original languageEnglish
Pages (from-to)27-34
Number of pages8
JournalJournal of Electroanalytical Chemistry
Volume676
DOIs
Publication statusPublished - Jul 1 2012

Fingerprint

Solid-state sensors
Ascorbic acid
Polymer films
Ascorbic Acid
Dopamine
Electrodes
Glassy carbon
Buffers
Phosphates
Surface roughness
Spectroscopy
Scanning
Thin films
Oxidation
Oxidation-Reduction

Keywords

  • Ascorbic acid
  • Conducting polymers
  • Dopamine
  • Polytyramine
  • Sensors

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Analytical Chemistry
  • Electrochemistry

Cite this

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title = "A solid state sensor based polytyramine film modified electrode for the determination of dopamine and ascorbic acid in a moderately acidic solution",
abstract = "A thin film of polytyramine (Pty) was deposited on the surface of a glassy carbon electrode (GCE) in phosphate buffer solution (pH = 4.1) by reversible potentiodynamic scans in the range of -200 mV to +1000 mV. The reactivity of the polymeric film was characterized using electrochemical methods in the presence of redox couple species and scan rate variations. The concentration of the generated polymeric film was 2.91 × 10 -10 mol cm -2 while the amount deposited during the entire repetitive cycles approaches 12.9 μg. The mean surface roughness estimated by Scanning Tunneling Spectroscopy (STM) technique is 0.7 nm, interestingly indicates the formation of a very thin layer. The modified electrode exhibited a substantial reactivity and high sensitivity in the oxidation of dopamine (DA) and ascorbic acid (AA). The symmetry and peak separation for both biological components were identified and the expected interference capacity by either component has been advantageously eliminated to a larger extent. The present working system provides a simple and fundamental approach for the simultaneous and selective determination of DA and AA with a detection limit brought down to 142 nM and 331 nM, respectively.",
keywords = "Ascorbic acid, Conducting polymers, Dopamine, Polytyramine, Sensors",
author = "Khudaish, {Emad A.} and Al-Ajmi, {Khawla Y.} and Al-Harthi, {Salim H.} and Al-Hinai, {Ashraf T.}",
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T1 - A solid state sensor based polytyramine film modified electrode for the determination of dopamine and ascorbic acid in a moderately acidic solution

AU - Khudaish, Emad A.

AU - Al-Ajmi, Khawla Y.

AU - Al-Harthi, Salim H.

AU - Al-Hinai, Ashraf T.

PY - 2012/7/1

Y1 - 2012/7/1

N2 - A thin film of polytyramine (Pty) was deposited on the surface of a glassy carbon electrode (GCE) in phosphate buffer solution (pH = 4.1) by reversible potentiodynamic scans in the range of -200 mV to +1000 mV. The reactivity of the polymeric film was characterized using electrochemical methods in the presence of redox couple species and scan rate variations. The concentration of the generated polymeric film was 2.91 × 10 -10 mol cm -2 while the amount deposited during the entire repetitive cycles approaches 12.9 μg. The mean surface roughness estimated by Scanning Tunneling Spectroscopy (STM) technique is 0.7 nm, interestingly indicates the formation of a very thin layer. The modified electrode exhibited a substantial reactivity and high sensitivity in the oxidation of dopamine (DA) and ascorbic acid (AA). The symmetry and peak separation for both biological components were identified and the expected interference capacity by either component has been advantageously eliminated to a larger extent. The present working system provides a simple and fundamental approach for the simultaneous and selective determination of DA and AA with a detection limit brought down to 142 nM and 331 nM, respectively.

AB - A thin film of polytyramine (Pty) was deposited on the surface of a glassy carbon electrode (GCE) in phosphate buffer solution (pH = 4.1) by reversible potentiodynamic scans in the range of -200 mV to +1000 mV. The reactivity of the polymeric film was characterized using electrochemical methods in the presence of redox couple species and scan rate variations. The concentration of the generated polymeric film was 2.91 × 10 -10 mol cm -2 while the amount deposited during the entire repetitive cycles approaches 12.9 μg. The mean surface roughness estimated by Scanning Tunneling Spectroscopy (STM) technique is 0.7 nm, interestingly indicates the formation of a very thin layer. The modified electrode exhibited a substantial reactivity and high sensitivity in the oxidation of dopamine (DA) and ascorbic acid (AA). The symmetry and peak separation for both biological components were identified and the expected interference capacity by either component has been advantageously eliminated to a larger extent. The present working system provides a simple and fundamental approach for the simultaneous and selective determination of DA and AA with a detection limit brought down to 142 nM and 331 nM, respectively.

KW - Ascorbic acid

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KW - Dopamine

KW - Polytyramine

KW - Sensors

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