A short review of some pharmacological, therapeutic and toxicological properties of praziquantel in man and animals.

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Abstract

Praziquantel is the current drug of choice against many trematodes and cestodes in both man and animals. This article summarizes the main pharmacological, therapeutic and toxicological properties of the drug, especially that have been reported during the last 10 years. In most cases, the effectiveness and safety of the drug have been confirmed, although there are currently concerns about the resistance/decreased effectiveness of the drug to certain Schistosome isolates, and also about the mutagenicity of the drug.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalPakistan Journal of Pharmaceutical Sciences
Volume19
Issue number2
Publication statusPublished - Apr 2006

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Praziquantel
Toxicology
Pharmacology
Pharmaceutical Preparations
Therapeutics
Cestoda
Safety

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Praziquantel is the current drug of choice against many trematodes and cestodes in both man and animals. This article summarizes the main pharmacological, therapeutic and toxicological properties of the drug, especially that have been reported during the last 10 years. In most cases, the effectiveness and safety of the drug have been confirmed, although there are currently concerns about the resistance/decreased effectiveness of the drug to certain Schistosome isolates, and also about the mutagenicity of the drug.",
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