A review of the use of Piper betel in oxidative stress disorders

C. Y. Lee, A. S. Nurul Zaidah, G. Nur Amalina, E. M.A. Muhammad Azree, S. Das, C. T. Zar*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Increase in prevalence of disease related oxidative stress disorders have been on the rise in the entire world since the past decades. Significant positive effects with few antioxidant properties in the modern drugs pave for the alternative medicines in managing the disease. Piper betel (P. betel), a herb, is known to possess high anti-oxidant, anti-diabetic, anti-atherosclerosis, anti-hyperlipidemic, anti-cancer and neuroprotective property. This review focused on the effect of P. betel on diabetes mellitus, atherosclerosis and chronic kidney disease, Alzheimer's disease and breast cancer. P. betel proved to show positive effects with specific outcomes towards these diseases. Moreover, the promising effect of P. betel in vitro studies was also highlighted in the present review. It is believed that the findings obtained in this review will draw the attention of the medical professionals and general public towards P. betel and it will open the door for further detailed research.

Original languageEnglish
Pages (from-to)269-277
Number of pages9
JournalClinica Terapeutica
Issue number5
Publication statusPublished - 2014
Externally publishedYes


  • Anti-oxidant
  • Herbs
  • Oxidative stress disorders
  • Piper betel

ASJC Scopus subject areas

  • Medicine(all)


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