A novel method for the synthesis of 4(3H)-quinazolinones

Raid J. Abdel-Jalil, Wolfgang Voelter, Muhammad Saeed

Research output: Contribution to journalArticle

212 Citations (Scopus)

Abstract

Condensation of anthranilamide with aryl, alkyl or heteroaryl aldehydes in refluxing ethanol and the presence of CuCl2 afforded the corresponding 2-substituted quinazolinones in excellent yields.

Original languageEnglish
Pages (from-to)3475-3476
Number of pages2
JournalTetrahedron Letters
Volume45
Issue number17
DOIs
Publication statusPublished - Apr 19 2004

Fingerprint

Quinazolinones
Aldehydes
Condensation
Ethanol
4-hydroxyquinazoline
anthranilamide
cupric chloride

Keywords

  • Anthranilimide
  • Quinazolinone
  • Schiff base
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

A novel method for the synthesis of 4(3H)-quinazolinones. / Abdel-Jalil, Raid J.; Voelter, Wolfgang; Saeed, Muhammad.

In: Tetrahedron Letters, Vol. 45, No. 17, 19.04.2004, p. 3475-3476.

Research output: Contribution to journalArticle

Abdel-Jalil, Raid J. ; Voelter, Wolfgang ; Saeed, Muhammad. / A novel method for the synthesis of 4(3H)-quinazolinones. In: Tetrahedron Letters. 2004 ; Vol. 45, No. 17. pp. 3475-3476.
@article{ebc9bce206144592bd343acd60df46da,
title = "A novel method for the synthesis of 4(3H)-quinazolinones",
abstract = "Condensation of anthranilamide with aryl, alkyl or heteroaryl aldehydes in refluxing ethanol and the presence of CuCl2 afforded the corresponding 2-substituted quinazolinones in excellent yields.",
keywords = "Anthranilimide, Quinazolinone, Schiff base, Synthesis",
author = "Abdel-Jalil, {Raid J.} and Wolfgang Voelter and Muhammad Saeed",
year = "2004",
month = "4",
day = "19",
doi = "10.1016/j.tetlet.2004.03.003",
language = "English",
volume = "45",
pages = "3475--3476",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "17",

}

TY - JOUR

T1 - A novel method for the synthesis of 4(3H)-quinazolinones

AU - Abdel-Jalil, Raid J.

AU - Voelter, Wolfgang

AU - Saeed, Muhammad

PY - 2004/4/19

Y1 - 2004/4/19

N2 - Condensation of anthranilamide with aryl, alkyl or heteroaryl aldehydes in refluxing ethanol and the presence of CuCl2 afforded the corresponding 2-substituted quinazolinones in excellent yields.

AB - Condensation of anthranilamide with aryl, alkyl or heteroaryl aldehydes in refluxing ethanol and the presence of CuCl2 afforded the corresponding 2-substituted quinazolinones in excellent yields.

KW - Anthranilimide

KW - Quinazolinone

KW - Schiff base

KW - Synthesis

UR - http://www.scopus.com/inward/record.url?scp=1842637263&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1842637263&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2004.03.003

DO - 10.1016/j.tetlet.2004.03.003

M3 - Article

AN - SCOPUS:1842637263

VL - 45

SP - 3475

EP - 3476

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 17

ER -