A new approach to homeostatic regulation: Towards a unified view of physiological and ecological concepts

Cédric L. Meunier, Arne M. Malzahn, Maarten Boersma

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Stoichiometric homeostasis is the ability of an organism to keep its body chemical composition constant, despite varying inputs. Stoichiometric homeostasis therefore constrains the metabolic needs of consumers which in turn often feed on resources not matching these requirements. In a broader context, homeostasis also relates to the capacity of an organism to maintain other biological parameters (e.g. body temperature) at a constant level over ambient environmental variations. Unfortunately, there are discrepancies in the literature and ecological and physiological definitions of homeostasis are disparate and partly contradictory. Here, we address this matter by reviewing the existing knowledge considering two distinct groups, regulators and conformers and, based on examples of thermo- and osmoregulation, we propose a new approach to stoichiometric homeostasis, unifying ecological and physiological concepts. We suggest a simple and precise graphical way to identify regulators and conformers: for any given biological parameter (e.g. nutrient stoichiometry, temperature), a sigmoidal relation between internal and external conditions can be observed for conformers while an inverse sigmoidal response is characteristic of regulators. This new definition and method, based on well-studied physiological mechanisms, unifies ecological and physiological approaches and is a useful tool for understanding how organisms are affected by and affect their environment.

Original languageEnglish
Article numbere107737
JournalPLoS One
Volume9
Issue number9
DOIs
Publication statusPublished - Sep 23 2014

Fingerprint

Physiological Phenomena
homeostasis
Homeostasis
Stoichiometry
Nutrients
organisms
Temperature
Osmoregulation
Chemical analysis
osmoregulation
stoichiometry
Body Composition
Body Temperature
body temperature
chemical composition
Food
nutrients
temperature

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

A new approach to homeostatic regulation : Towards a unified view of physiological and ecological concepts. / Meunier, Cédric L.; Malzahn, Arne M.; Boersma, Maarten.

In: PLoS One, Vol. 9, No. 9, e107737, 23.09.2014.

Research output: Contribution to journalArticle

Meunier, Cédric L. ; Malzahn, Arne M. ; Boersma, Maarten. / A new approach to homeostatic regulation : Towards a unified view of physiological and ecological concepts. In: PLoS One. 2014 ; Vol. 9, No. 9.
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