Abstract
Ketones can be reduced in the presence of conjugated enones by sodiumborohydride in 50% methanol in dichloromethane at -78°C. The selectivity is generally excellent. In favorable cases the reaction can be carried out at room temperature in dichloromethane with acetic acid as catalyst.
Original language | English |
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Pages (from-to) | 517-520 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 29 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1988 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry