Abstract
The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.
| Original language | English |
|---|---|
| Pages (from-to) | 1631-1648 |
| Number of pages | 18 |
| Journal | Future Medicinal Chemistry |
| Volume | 9 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - Sep 1 2017 |
Keywords
- biodiversity
- chemodiversity
- fungi
- polyketides
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology
- Drug Discovery
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Cite this
Hussain, H., Al-Sadi, A. M., Schulz, B., Steinert, M., Khan, A., Green, I. R., & Ahmed, I. (2017). A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity. Future Medicinal Chemistry, 9(14), 1631-1648. https://doi.org/10.4155/fmc-2017-0028