Abstract
The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.
| Original language | English |
|---|---|
| Pages (from-to) | 1631-1648 |
| Number of pages | 18 |
| Journal | Future Medicinal Chemistry |
| Volume | 9 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - Sep 1 2017 |
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Keywords
- biodiversity
- chemodiversity
- fungi
- polyketides
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology
- Drug Discovery
Cite this
A fruitful decade for fungal polyketides from 2007 to 2016 : Antimicrobial activity, chemotaxonomy and chemodiversity. / Hussain, Hidayat; Al-Sadi, Abdullah M.; Schulz, Barbara; Steinert, Michael; Khan, Ajmal; Green, Ivan R.; Ahmed, Ishtiaq.
In: Future Medicinal Chemistry, Vol. 9, No. 14, 01.09.2017, p. 1631-1648.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - A fruitful decade for fungal polyketides from 2007 to 2016
T2 - Antimicrobial activity, chemotaxonomy and chemodiversity
AU - Hussain, Hidayat
AU - Al-Sadi, Abdullah M.
AU - Schulz, Barbara
AU - Steinert, Michael
AU - Khan, Ajmal
AU - Green, Ivan R.
AU - Ahmed, Ishtiaq
PY - 2017/9/1
Y1 - 2017/9/1
N2 - The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.
AB - The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.
KW - biodiversity
KW - chemodiversity
KW - fungi
KW - polyketides
UR - http://www.scopus.com/inward/record.url?scp=85029932446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85029932446&partnerID=8YFLogxK
U2 - 10.4155/fmc-2017-0028
DO - 10.4155/fmc-2017-0028
M3 - Review article
VL - 9
SP - 1631
EP - 1648
JO - Future Medicinal Chemistry
JF - Future Medicinal Chemistry
SN - 1756-8919
IS - 14
ER -