A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity

Hidayat Hussain; Abdullah M. Al-Sadi; Barbara Schulz; Michael Steinert; Ajmal Khan; Ivan R. Green; Ishtiaq Ahmed

doi:10.4155/fmc-2017-0028

A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity

Hidayat Hussain^*, Abdullah M. Al-Sadi, Barbara Schulz, Michael Steinert, Ajmal Khan, Ivan R. Green, Ishtiaq Ahmed

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

15 Citations (Scopus)

Abstract

The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.

Original language	English
Pages (from-to)	1631-1648
Number of pages	18
Journal	Future Medicinal Chemistry
Volume	9
Issue number	14
DOIs	https://doi.org/10.4155/fmc-2017-0028
Publication status	Published - Sept 2017

Keywords

biodiversity
chemodiversity
fungi
polyketides

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Drug Discovery

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title = "A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity",

abstract = "The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.",

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AU - Schulz, Barbara

AU - Steinert, Michael

AU - Khan, Ajmal

AU - Green, Ivan R.

AU - Ahmed, Ishtiaq

PY - 2017/9

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AB - The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.

KW - biodiversity

KW - chemodiversity

KW - fungi

KW - polyketides

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A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity

Abstract

Keywords

ASJC Scopus subject areas

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