A fruitful decade for fungal polyketides from 2007 to 2016: Antimicrobial activity, chemotaxonomy and chemodiversity

Hidayat Hussain*, Abdullah M. Al-Sadi, Barbara Schulz, Michael Steinert, Ajmal Khan, Ivan R. Green, Ishtiaq Ahmed

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)

Abstract

The last three decades have shown that the fungi can be 'biofactories' of novel, bioactive secondary metabolites that produce numerous natural products with novel skeletons and biological activities. Particularly in the last 10 years, large numbers of antimicrobial fungal secondary metabolites have been discovered. This review provides an overview of key, defining developments of the last 10 years regarding the discovery of antimicrobial activity, chemotaxonomy and chemodiversity of fungal polyketides.

Original languageEnglish
Pages (from-to)1631-1648
Number of pages18
JournalFuture Medicinal Chemistry
Volume9
Issue number14
DOIs
Publication statusPublished - Sep 2017

Keywords

  • biodiversity
  • chemodiversity
  • fungi
  • polyketides

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery

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