Abstract
In this short note communication, we report the synthesis of a novel amide 4’-methyl-2’-(quinolin-8-ylcarbamoyl)-biphenyl-4-carboxylic acid ethyl ester by the Ru-catalyzed C(sp2)-H bond arylation reaction. The catalytic C-H bond functionalization reaction was employed, amongst other reaction reagents and conditions, [RuCl2(p-cymene)]2 as a precatalyst and (p-tol)3P as a ligand. The arylation product was characterized by various spectroscopic methods (1H NMR,13C NMR, IR, GC-MS, and IR spectroscopy), and its composition was confirmed by elemental analysis.
Original language | English |
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Article number | M1132 |
Journal | MolBank |
Volume | 2020 |
Issue number | 2 |
DOIs |
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Publication status | Published - May 2020 |
Keywords
- Benzamides
- Bidentate directing groups
- C-H bond functionalization
- Catalysis
- Chelation assistance
- Organic synthesis
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry