Abstract
The importance of conjugate addition reactions with organocopper reagents has increased since the seminal synthetic application, as reported by Robinson in the early 1940s. This review chapter is intended to provide an overview of substrate-controlled diastereoselective conjugate organocuprate addition reactions, utilized in the preparation of complex natural products on selected syntheses which have been published within the past decade.
Original language | English |
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Title of host publication | Synthetic Methods I - Chiral Pool and Diastereoselective Methods |
Publisher | Elsevier Ltd |
Pages | 441-471 |
Number of pages | 31 |
Volume | 2 |
ISBN (Print) | 9780080951683 |
DOIs | |
Publication status | Published - Sept 2012 |
Externally published | Yes |
Keywords
- Complex natural products
- Diastereoselective conjugate organocuprate addition reactions
- Organocopper reagents
ASJC Scopus subject areas
- General Chemistry