2.15 Selected Diastereoselective Reactions: Substrate Controlled Stereoselective Conjugate Addition Reactions with Organocopper Reagents

P. Siengalewicz*, J. Mulzer, U. Rinner

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

The importance of conjugate addition reactions with organocopper reagents has increased since the seminal synthetic application, as reported by Robinson in the early 1940s. This review chapter is intended to provide an overview of substrate-controlled diastereoselective conjugate organocuprate addition reactions, utilized in the preparation of complex natural products on selected syntheses which have been published within the past decade.

Original languageEnglish
Title of host publicationSynthetic Methods I - Chiral Pool and Diastereoselective Methods
PublisherElsevier Ltd
Pages441-471
Number of pages31
Volume2
ISBN (Print)9780080951683
DOIs
Publication statusPublished - Sept 2012
Externally publishedYes

Keywords

  • Complex natural products
  • Diastereoselective conjugate organocuprate addition reactions
  • Organocopper reagents

ASJC Scopus subject areas

  • General Chemistry

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