Elias Said

Dr.

Former affiliation
  • 2787 Citations
  • 17 h-Index
20022018
If you made any changes in Pure these will be visible here soon.

Research Output 2002 2018

  • 2787 Citations
  • 17 h-Index
  • 36 Article
  • 2 Review article
  • 1 Chapter
  • 1 Editorial
2018

Immune Responses to RNA Viruses

Said, E., Diaz-Griffero, F., Bonte, D., Lamarre, D. & Al-Jabri, A., Jan 1 2018, In : Journal of Immunology Research. 2018, 1 p.

Research output: Contribution to journalEditorial

RNA Viruses
7 Citations (Scopus)

Viruses Seen by Our Cells: The Role of Viral RNA Sensors

Said, E., Tremblay, N., Al-Balushi, M., Al-Jabri, A. & Lamarre, D., Jan 1 2018, In : Journal of Immunology Research. 2018, 1 p.

Research output: Contribution to journalReview article

Viral RNA
Antiviral Agents
Toll-Like Receptor 8
Toll-Like Receptor 7
Toll-Like Receptor 3
2017
4 Citations (Scopus)

Altered blood cytokines, CD4 T cells, NK and neutrophils in patients with obstructive sleep apnea

Said, E. A., Al-Abri, M. A., Al-Saidi, I., Al-Balushi, M. S., Al-Busaidi, J. Z., Al-Reesi, I., Koh, C. Y., Hasson, S. S., Idris, M. A., Al-Jabri, A. A. & Habbal, O., Oct 1 2017, In : Immunology Letters. 190, p. 272-278 7 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Neutrophils
Cytokines
T-Lymphocytes
Natural Killer Cells
2016
2 Citations (Scopus)

A potential inhibitory profile of liver CD68+ cells during HCV infection as observed by an increased CD80 and PD-L1 but not CD86 expression

Said, E. A., Al-Reesi, I., Al-Riyami, M., Al-Naamani, K., Al-Sinawi, S., Al-Balushi, M. S., Koh, C. Y., Al-Busaidi, J. Z., Idris, M. A. & Al-Jabri, A. A., Apr 1 2016, In : PLoS One. 11, 4, e0153191.

Research output: Contribution to journalArticle

Liver
hepatocytes
Infection
infection
liver
2 Citations (Scopus)

Frequency of TLR4 (1063A/G and 1363C/T) polymorphisms in healthy and HIV-infected Omani individuals and their relationship to viral load and T cell count

Said, E. A., Al-Yafei, F., Zadjali, F., Al-Balushi, M. S., Hasson, S. S., Al-Mahroqi, S. H., Koh, C. Y., Al-Naamani, K., Al-Busaidi, J. Z., Idris, M. A., Balkhair, A. & Al-Jabri, A. A., Apr 4 2016, In : Genetics and Molecular Research. 15, 2, 15027671.

Research output: Contribution to journalArticle

CD4 Lymphocyte Count
Viral Load
Single Nucleotide Polymorphism
Cell Count
HIV
12 Citations (Scopus)

HCV RNA Activates APCs via TLR7/TLR8 while Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses

Zhang, Y., El-Far, M., Dupuy, F. P., Abdel-Hakeem, M. S., He, Z., Procopio, F. A., Shi, Y., Haddad, E. K., Ancuta, P., Sekaly, R. P. & Said, E. A., Jul 7 2016, In : Scientific Reports. 6, 29447.

Research output: Contribution to journalArticle

Antiviral Agents
Toll-Like Receptor 8
Toll-Like Receptor 7
Macrophages
RNA
2 Citations (Scopus)
Helicobacter pylori
Immunoglobulin A
Pregnancy
Immunoglobulin M
Antibodies
11 Citations (Scopus)

Increased CD86 but Not CD80 and PD-L1 expression on liver CD68+ cells during chronic HBV infection

Said, E. A., Al-Reesi, I., Al-Riyami, M., Al-Naamani, K., Al-Sinawi, S., Al-Balushi, M. S., Koh, C. Y., Al-Busaidi, J. Z., Idris, M. A. & Al-Jabri, A. A., Jun 1 2016, In : PLoS One. 11, 6, e0158265.

Research output: Contribution to journalArticle

Liver
hepatocytes
Infection
infection
T-cells
2015
7 Citations (Scopus)

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation

El-Far, M., Ancuta, P., Routy, J. P., Zhang, Y., Bakeman, W., Bordi, R., DaFonseca, S., Said, E. A., Gosselin, A., Tep, T. S., Eichbaum, Q., van Grevenynghe, J., Schwartz, O., Freeman, G. J., Haddad, E. K., Chomont, N. & Sékaly, R. P., 2015, In : Journal of General Virology. 96, p. 1463-1477 15 p.

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
HIV
Virus Diseases
Down-Regulation
2014
15 Citations (Scopus)
HIV Infections
Single Nucleotide Polymorphism
Cell Count
Genotype
HIV
1 Citation (Scopus)

Connaissances, attitudes et comportements souhaités concernant le dépistage du VIH et l'autoprotection: Une enquête auprès de femmes enceintes omanaises

Translated title of the contribution: Knowledge, attitudes and intended behaviours towards HIV testing and self-protection: a survey of Omani pregnant womenAl-Jabri, A. A., Youssef, R. M., Hasson, S. S., Al-Belushi, M., Balkhair, A. A., Al-Saadoon, M., Mathew, M., Al-Mahroqi, S., Said, E., Koh, C. Y. & Idris, M. A., Oct 1 2014, In : Eastern Mediterranean Health Journal. 20, 10, p. 614-622 9 p.

Research output: Contribution to journalArticle

Pregnant Women
HIV
Oman
Disclosure
Antiviral Agents
4 Citations (Scopus)

Fluctuation in the levels of immunoglobulin m and immunoglobulin G antibodies for cardiolipin and β2-glycoprotein among healthy pregnant women

Al-Balushi, M. S., Hasson, S. S., Said, E. A., Al-Busaidi, J. Z., Al-Daihani, M. S., Othman, M. S., Sallam, T. A., Idris, M. A., Al-Kalbani, M., Woodhouse, N. & Al-Jabri, A. A., Nov 1 2014, In : Sultan Qaboos University Medical Journal. 14, 4, p. e478-e485

Research output: Contribution to journalArticle

Cardiolipins
Immunoglobulins
Pregnant Women
Glycoproteins
Immunoglobulin G
2 Citations (Scopus)

High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy

Hasson, S. S. A., Al-Balushi, M. S., Al Yahmadi, M. H., Al-Busaidi, J. Z., Said, E. A., Othman, M. S., Sallam, T. A., Idris, M. A. & Al-Jabri, A. A., 2014, In : Asian Pacific Journal of Tropical Biomedicine. 4, 8, p. 610-613 4 p.

Research output: Contribution to journalArticle

Zinc
Glycoproteins
Acquired Immunodeficiency Syndrome
Blood
Immunosorbents
1 Citation (Scopus)

HLA-A68 and HLA-B15 alleles correlate with poor immune response among AIDS patients on combined antiretroviral therapy

El-Beeli, M., Al-Mahrooqi, S. H., Youssef, R. M., Zadjali, F., Balkhair, A., Al-Balushi, M. S., Said, E. A., Hasson, S. S. & Al-Jabri, A. A., Feb 5 2014, (Accepted/In press) In : Human Immunology.

Research output: Contribution to journalArticle

HLA-B15 Antigen
Acquired Immunodeficiency Syndrome
Alleles
Viral Load
HIV-1
2 Citations (Scopus)
CCR Receptors
Population
Genes
Chemokines
Ethnic Groups
2013
10 Citations (Scopus)

Evaluation of anti-resistant activity of Auklandia(Saussurea lappa) root against some human pathogens

Hasson, S. S. A., Al-Balushi, M. S., KhazinaAlharthy, Al-Busaidi, J., MunaSulimanAldaihani, Othman, M. S., Said, E. A., Habal, O., Sallam, T. A., Aljabri, A. A. & AhmedIdris, M., Jul 2013, In : Asian Pacific Journal of Tropical Biomedicine. 3, 7, p. 557-562 6 p.

Research output: Contribution to journalArticle

Saussurea
Plant Roots
Plant Extracts
Pathogens
Agar
12 Citations (Scopus)

Sustained hyperresponsiveness of dendritic cells is associated with spontaneous resolution of acute hepatitis C

Pelletier, S., Bédard, N., Said, E., Ancuta, P., Bruneau, J. & Shoukry, N. H., Jun 2013, In : Journal of Virology. 87, 12, p. 6769-6781 13 p.

Research output: Contribution to journalArticle

hepatitis C
Hepatitis C virus
dendritic cells
Hepatitis C
Hepacivirus
2012

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis (Journal of Clinical Investigation (2011) 121, 10 (3877-3888) DOI: 10.1172/JCI59211)

Van Grevenynghe, J., Cubas, R. A., Noto, A., DaFonseca, S., He, Z., Peretz, Y., Filali-Mouhim, A., Dupuy, F. P., Procopio, F. A., Chomont, N., Balderas, R. S., Said, E. A., Boulassel, M. R., Tremblay, C. L., Routy, J. P., Sékaly, R. P. & Haddad, E. K., Jul 2 2012, In : Journal of Clinical Investigation. 122, 7, p. 2704 1 p.

Research output: Contribution to journalArticle

Memory Disorders
HIV Infections
B-Lymphocytes
Apoptosis
5 Citations (Scopus)
Hibiscus
Venoms
Guinea Pigs
Hemorrhage
Plant Extracts

The importance of autoantibodies in the etiology, pathogenesis and diagnosis of autoimmune diseases

Al-Jabri, A. A., Said, E., Koh, C., Al-Buloshi, M. S. & Hasson, S. S., 2012, Autoantibodies: Detection, Pathogenicity and Health Implications. Nova Science Publishers, Inc., p. 109-135 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Autoantibodies
Autoimmune Diseases
Rheumatoid Arthritis
Inflammation
Antibodies
2011
74 Citations (Scopus)

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis

Van Grevenynghe, J., Cubas, R. A., Noto, A., DaFonseca, S., He, Z., Peretz, Y., Filali-Mouhim, A., Dupuy, F. P., Procopio, F. A., Chomont, N., Balderas, R. S., Said, E. A., Boulassel, M. R., Tremblay, C. L., Routy, J. P., Sékaly, R. P. & Haddad, E. K., Oct 3 2011, In : Journal of Clinical Investigation. 121, 10, p. 3877-3888 12 p.

Research output: Contribution to journalArticle

Memory Disorders
HIV Infections
B-Lymphocytes
Apoptosis
Cell Survival
75 Citations (Scopus)

Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7

Monteiro, P., Gosselin, A., Wacleche, V. S., El-Far, M., Said, E. A., Kared, H., Grandvaux, N., Boulassel, M. R., Routy, J. P. & Ancuta, P., Apr 15 2011, In : Journal of Immunology. 186, 8, p. 4618-4630 13 p.

Research output: Contribution to journalArticle

Integrins
HIV Infections
HIV-1
T-Lymphocytes
Permissiveness
2010
164 Citations (Scopus)

Peripheral blood CCR4+CCR6+ and CXCR3 +CCR6+ CD4+ T cells are highly permissive to HIV-1 infection

Gosselin, A., Monteiro, P., Chomont, N., Diaz-Griffero, F., Said, E. A., Fonseca, S., Wacleche, V., El-Far, M., Boulassel, M. R., Routy, J. P., Sekaly, R. P. & Ancuta, P., Feb 1 2010, In : Journal of Immunology. 184, 3, p. 1604-1616 13 p.

Research output: Contribution to journalArticle

HIV Infections
HIV-1
T-Lymphocytes
HIV
T-Lymphocyte Subsets
256 Citations (Scopus)

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4 + T cell activation during HIV infection

Said, E. A., Dupuy, F. P., Trautmann, L., Zhang, Y., Shi, Y., El-Far, M., Hill, B. J., Noto, A., Ancuta, P., Peretz, Y., Fonseca, S. G., Van Grevenynghe, J., Boulassel, M. R., Bruneau, J., Shoukry, N. H., Routy, J. P., Douek, D. C., Haddad, E. K. & Sekaly, R. P., Apr 2010, In : Nature Medicine. 16, 4, p. 452-459 8 p.

Research output: Contribution to journalArticle

T-cells
Interleukin-10
HIV Infections
Monocytes
Chemical activation
1 Citation (Scopus)
Hepacivirus
RNA
Therapeutics
Chronic Hepatitis C
Virus Diseases
2009

P16-54 LB. Blood CCR6+ Th17 and Th1Th17 but not CCR6neg Th1 cells are targets for HIV replication and their frequency is diminished in HIV-infected subjects

Gosselin, A., Monteiro, P., Chomont, N., Diaz-Griffero, F., Wacleche, V. S., Said, E. A., Fonseca, S., El-Far, M., Boulassel, M., Routy, J., Sekaly, R. & Ancuta, P., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, 1742.

Research output: Contribution to journalArticle

Th1 Cells
HIV
34 Citations (Scopus)

Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI

Dekaban, G. A., Snir, J., Shrum, B., De Chickera, S., Willert, C., Merrill, M., Said, E. A., Sekaly, R. P., Foster, P. J. & O'Connell, P. J., Apr 2009, In : Journal of Immunotherapy. 32, 3, p. 240-251 12 p.

Research output: Contribution to journalArticle

Dendritic Cells
Cell Movement
Vaccines
Therapeutics
Magnetic Resonance Spectroscopy
2008
24 Citations (Scopus)

Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection

van Grevenynghe, J., Halwani, R., Chomont, N., Ancuta, P., Peretz, Y., Tanel, A., Procopio, F. A., shi, Y., Said, E. A., Haddad, E. K. & Sekaly, R. P., Jun 2008, In : Seminars in Immunology. 20, 3, p. 196-203 8 p.

Research output: Contribution to journalArticle

HIV Infections
B-Lymphocytes
Lymph Nodes
Lymphoid Tissue
Virus Diseases
54 Citations (Scopus)

T-cell exhaustion in HIV infection

El-Far, M., Halwani, R., Said, E., Trautmann, L., Doroudchi, M., Janbazian, L., Fonseca, S., Van Grevenynghe, J., Yassine-Diab, B., Sékaly, R. P. & Haddad, E. K., Feb 2008, In : Current HIV/AIDS Reports. 5, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

HIV Infections
T-Lymphocytes
HIV
CD4 Antigens
Virus Diseases
118 Citations (Scopus)

Transcription factor FOXO3a controls the persistence of memory CD4 + T cells during HIV infection

Van Grevenynghe, J., Procopio, F. A., He, Z., Chomont, N., Riou, C., Zhang, Y., Gimmig, S., Boucher, G., Wilkinson, P., Shi, Y., Yassine-Diab, B., Said, E. A., Trautmann, L., Far, M. E., Balderas, R. S., Boulassel, M. R., Routy, J. P., Haddad, E. K. & Sekaly, R. P., Mar 2008, In : Nature Medicine. 14, 3, p. 266-274 9 p.

Research output: Contribution to journalArticle

T-cells
HIV Infections
Transcription Factors
T-Lymphocytes
Data storage equipment
381 Citations (Scopus)

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

Gaucher, D., Therrien, R., Kettaf, N., Angermann, B. R., Boucher, G., Filali-Mouhim, A., Moser, J. M., Mehta, R. S., Drake, D. R., Castro, E., Akondy, R., Rinfret, A., Yassine-Diab, B., Said, E. A., Chouikh, Y., Cameron, M. J., Clum, R., Kelvin, D., Somogyi, R., Greller, L. D. & 6 others, Balderas, R. S., Wilkinson, P., Pantaleo, G., Tartaglia, J., Haddad, E. K. & Sekaly, R. P., Dec 22 2008, In : Journal of Experimental Medicine. 205, 13, p. 3119-3131 13 p.

Research output: Contribution to journalArticle

Yellow Fever Vaccine
Vaccines
Immune System
Vaccination
Viral Vaccines
2007
17 Citations (Scopus)

Programmed death 1: A critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections

Trautmann, L., Said, E. A., Halwani, R., Janbazian, L., Chomont, N., El-Far, M., Breton, G., Haddad, E. K. & Sekaly, R. P., May 2007, In : Current Opinion in HIV and AIDS. 2, 3, p. 219-227 9 p.

Research output: Contribution to journalArticle

Virus Diseases
Immunotherapy
T-Lymphocytes
HIV
Cytokines
2006
9 Citations (Scopus)

Erratum: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction (Nature Medicine (2006) 12 (1198-1202))

Trautmann, L., Janbazian, L., Chomont, N., Said, E. A., Gimmig, S., Bessette, B., Boulassel, M. R., Delwart, E., Sepulveda, H., Balderas, R. S., Routy, J. P., Haddad, E. K. & Sekaly, R. P., Nov 2006, In : Nature Medicine. 12, 11, p. 1329 1 p.

Research output: Contribution to journalArticle

Up-Regulation
Medicine
HIV
T-Lymphocytes
22 Citations (Scopus)

Generation and maintenance of human memory cells during viral infection

Halwani, R., Doroudchi, M., Yassine-Diab, B., Janbazian, L., Shi, Y., Said, E. A., Haddad, E. K. & Sékaly, R. P., Nov 2006, In : Springer Seminars in Immunopathology. 28, 3, p. 197-208 12 p.

Research output: Contribution to journalArticle

Virus Diseases
Infection
T-Lymphocytes
Viruses
Measles virus
996 Citations (Scopus)

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

Trautmann, L., Janbazian, L., Chomont, N., Said, E. A., Gimmig, S., Bessette, B., Boulassel, M. R., Delwart, E., Sepulveda, H., Balderas, R. S., Routy, J. P., Haddad, E. K. & Sekaly, R. P., Oct 2006, In : Nature Medicine. 12, 10, p. 1198-1202 5 p.

Research output: Contribution to journalArticle

T-cells
Up-Regulation
HIV
T-Lymphocytes
Cytokines
2005
62 Citations (Scopus)

Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin

Said, E. A., Courty, J., Svab, J., Delbé, J., Krust, B. & Hovanessian, A. G., Sep 2005, In : FEBS Journal. 272, 18, p. 4646-4659 14 p.

Research output: Contribution to journalArticle

HIV Infections
HIV-1
Confocal Microscopy
pleiotrophin
nucleolin
2004
164 Citations (Scopus)

Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells

Legrand, D., Vigié, K., Said, E. A., Elass, E., Masson, M., Slomianny, M. C., Carpentier, M., Briand, J. P., Mazurier, J. & Hovanessian, A. G., Jan 2004, In : European Journal of Biochemistry. 271, 2, p. 303-317 15 p.

Research output: Contribution to journalArticle

Lactoferrin
Endocytosis
Proteoglycans
nucleolin
Viruses
60 Citations (Scopus)

The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection

Hovanessian, A. G., Briand, J. P., Said, E. A., Svab, J., Ferris, S., Dali, H., Muller, S., Desgranges, C. & Krust, B., Nov 2004, In : Immunity. 21, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

B-Lymphocyte Epitopes
Caveolin 1
Virus Diseases
HIV-1
Glycoproteins
2002
110 Citations (Scopus)

The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor

Said, E. A., Krust, B., Nisole, S., Svab, J., Briand, J. P. & Hovanessian, A. G., Oct 4 2002, In : Journal of Biological Chemistry. 277, 40, p. 37492-37502 11 p.

Research output: Contribution to journalArticle

HIV
Cytokines
Confocal Microscopy
GPI-Linked Proteins
Binding Sites
67 Citations (Scopus)

The anti-HIV pentameric pseudopeptide HB-19 binds the C-terminal end of nucleolin and prevents anchorage of virus particles in the plasma membrane of target cells

Nisole, S., Said, E. A., Mische, C., Prevost, M. C., Krust, B., Bouvet, P., Bianco, A., Briandand, J. P. & Hovanessian, A. G., Jun 7 2002, In : Journal of Biological Chemistry. 277, 23, p. 20877-20886 10 p.

Research output: Contribution to journalArticle

Cell membranes
Viruses
Virion
Cell Membrane
HIV