Triterpenoids from the leaves of Psidium guajava

Sabira Begum; Syed Imran Hassan; Bina S. Siddiqui; Farhana Shaheen; M. Nabeel Ghayur; Anwar H. Gilani

doi:10.1016/S0031-9422(02)00190-5

Triterpenoids from the leaves of Psidium guajava

Sabira Begum^*, Syed Imran Hassan, Bina S. Siddiqui, Farhana Shaheen, M. Nabeel Ghayur, Anwar H. Gilani

^*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلة › Article › مراجعة النظراء

107 اقتباسات (Scopus)

ملخص

Two triterpenoids, 20β-acetoxy-2α,3β-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2α,3β-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2α-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and β-sitosterol-3-O-β-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 μg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.

اللغة الأصلية	English
الصفحات (من إلى)	399-403
عدد الصفحات	5
دورية	Phytochemistry
مستوى الصوت	61
رقم الإصدار	4
المعرِّفات الرقمية للأشياء	https://doi.org/10.1016/S0031-9422(02)00190-5
حالة النشر	Published - أكتوبر 2002
منشور خارجيًا	نعم

ASJC Scopus subject areas

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الوصول إلى المستند

10.1016/S0031-9422(02)00190-5

الملفات والروابط الأخرى

Link to publication in Scopus

قم بذكر هذا

@article{3177afbe444e40dfb5ad7684dec1ff01,

title = "Triterpenoids from the leaves of Psidium guajava",

abstract = "Two triterpenoids, 20β-acetoxy-2α,3β-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2α,3β-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2α-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and β-sitosterol-3-O-β-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 μg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.",

keywords = "Guavacoumaric acid, Guavanoic acid, Psidium guajava, Spasmolytic activity, Triterpenoids",

author = "Sabira Begum and Hassan, {Syed Imran} and Siddiqui, {Bina S.} and Farhana Shaheen and {Nabeel Ghayur}, M. and Gilani, {Anwar H.}",

year = "2002",

month = oct,

doi = "10.1016/S0031-9422(02)00190-5",

language = "English",

volume = "61",

pages = "399--403",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Limited",

number = "4",

}

TY - JOUR

T1 - Triterpenoids from the leaves of Psidium guajava

AU - Begum, Sabira

AU - Hassan, Syed Imran

AU - Siddiqui, Bina S.

AU - Shaheen, Farhana

AU - Nabeel Ghayur, M.

AU - Gilani, Anwar H.

PY - 2002/10

Y1 - 2002/10

N2 - Two triterpenoids, 20β-acetoxy-2α,3β-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2α,3β-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2α-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and β-sitosterol-3-O-β-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 μg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.

AB - Two triterpenoids, 20β-acetoxy-2α,3β-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2α,3β-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2α-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and β-sitosterol-3-O-β-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 μg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.

KW - Guavacoumaric acid

KW - Guavanoic acid

KW - Psidium guajava

KW - Spasmolytic activity

KW - Triterpenoids

UR - http://www.scopus.com/inward/record.url?scp=0036774814&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036774814&partnerID=8YFLogxK

U2 - 10.1016/S0031-9422(02)00190-5

DO - 10.1016/S0031-9422(02)00190-5

M3 - Article

C2 - 12377233

AN - SCOPUS:0036774814

SN - 0031-9422

VL - 61

SP - 399

EP - 403

JO - Phytochemistry

JF - Phytochemistry

IS - 4

ER -

Triterpenoids from the leaves of Psidium guajava

ملخص

ASJC Scopus subject areas

الوصول إلى المستند

الملفات والروابط الأخرى

بصمة

قم بذكر هذا