TY - JOUR
T1 - The successful use of mycophenolate mofetil in a patient with active birdshot chorio-retinopathy refractory to azathioprine therapy - Case report
AU - Vianna, Raul N.G.
AU - Al-Kharusi, Nadia
AU - Deschênes, Jean
PY - 2004
Y1 - 2004
N2 - Report on the effect of oral mycophenolate mofetil (MMF) on the treatment of a patient with active birdshot chorioretinopathy (BC) refractory to azathioprine (AZA) therapy. A sixty-two-year-old female patient with BC developed cystoid macular edema (CME) and severe retinal vasculitis in both eyes. AZA (2 mg/kg/day) was then initially prescribed in order to control the inflammatory process. As AZA failed to control the intraocular inflammation after one year, it was replaced by MMF (2 mg/kg/day), which controlled the inflammatory process and improved the patient's visual acuity. In three years under MMF, no recurrence was observed and her vision remained unchanged. In our patient with active BC refractory to AZA, MMF was effective to decrease the intraocular inflammation, as well as to improve the patient's visual acuity.
AB - Report on the effect of oral mycophenolate mofetil (MMF) on the treatment of a patient with active birdshot chorioretinopathy (BC) refractory to azathioprine (AZA) therapy. A sixty-two-year-old female patient with BC developed cystoid macular edema (CME) and severe retinal vasculitis in both eyes. AZA (2 mg/kg/day) was then initially prescribed in order to control the inflammatory process. As AZA failed to control the intraocular inflammation after one year, it was replaced by MMF (2 mg/kg/day), which controlled the inflammatory process and improved the patient's visual acuity. In three years under MMF, no recurrence was observed and her vision remained unchanged. In our patient with active BC refractory to AZA, MMF was effective to decrease the intraocular inflammation, as well as to improve the patient's visual acuity.
KW - Azathioprine/therapeutic use
KW - Case report [Publication type]
KW - Chorioretinitis/drug therapy
KW - Choroid diseases/drug therapy
KW - Mycophenolic acid/therapeutic use
KW - Retinal vasculitis
UR - http://www.scopus.com/inward/record.url?scp=77952767146&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952767146&partnerID=8YFLogxK
U2 - 10.1590/S0004-27492004000600022
DO - 10.1590/S0004-27492004000600022
M3 - Article
AN - SCOPUS:77952767146
SN - 0004-2749
VL - 67
SP - 957
EP - 959
JO - Arquivos Brasileiros de Oftalmologia
JF - Arquivos Brasileiros de Oftalmologia
IS - 6
ER -