TY - JOUR
T1 - Synthesis and properties of some 2, 3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines
AU - Abdel-Jalil, Raid J.
AU - Al-Qawasmeh, Raed A.
AU - Voelter, Wolfgang
AU - Heeg, Peter
AU - El-Abadelah, Mustafa M.
AU - Sabri, Salim S.
PY - 2000
Y1 - 2000
N2 - The 2, 3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1, 2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
AB - The 2, 3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1.2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1, 2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coti ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC 10231.
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U2 - 10.1002/jhet.5570370541
DO - 10.1002/jhet.5570370541
M3 - Article
AN - SCOPUS:0033756483
SN - 0022-152X
VL - 37
SP - 1273
EP - 1275
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
IS - 5
ER -