TY - JOUR
T1 - Short-term efficacy of selective laser trabeculoplasty in omani eyes with glaucoma
T2 - A single institutional study
AU - Busaidi, Aisha Al
AU - Shenoy, Kashinatha
AU - Panchatcharam, Sathiya Murthi
AU - Al-Mujaini, Abdullah
N1 - Publisher Copyright:
© 2020 Al Busaidi et al.
PY - 2020
Y1 - 2020
N2 - Purpose: There is some evidence suggesting a different nature of response to selective laser trabeculoplasty (SLT) among different races. Therefore, we aimed to assess the short-term efficacy, safety and nature of outcome of SLT in Omani eyes. Patients and Methods: A retrospective review was performed of patients with open-angle glaucoma (OAG) or ocular hypertension (OHTN) who underwent a single session of 360-degree SLT between January 1, 2017 and December 31, 2018. The main outcome was mean IOP reduction and attainment of treatment success at 5 weeks and 12 weeks post treatment defined as at least 20% IOP reduction from baseline without further medications or inter-ventions. Secondary outcomes were frequency of adverse events and factors predicting success. Results: A total of 33 eyes of 33 Omani patients who underwent treatment with SLT were analyzed. The nature of response to laser followed a gradual pattern as the mean IOP reduction from baseline was 20.2% (5.21 mm Hg, P <0.001) at 5 weeks and further enhanced to 27.2% (6.95 mm Hg, P <0.001) at 12 weeks. Short-term success was achieved in 51.5% and 72.2% of eyes at 5 and 12 weeks, respectively. SLT was most effective in OHTN subgroup and those with higher baseline IOP (both P <0.001). Side effects were an infre-quent occurrence, minor and transient. Conclusion: The short-term success of SLT in Omani eyes was clinically relevant and comparable to the gradual pattern seen in patients of Indian ancestry. It is a safe therapeutic option in selective Omani eyes.
AB - Purpose: There is some evidence suggesting a different nature of response to selective laser trabeculoplasty (SLT) among different races. Therefore, we aimed to assess the short-term efficacy, safety and nature of outcome of SLT in Omani eyes. Patients and Methods: A retrospective review was performed of patients with open-angle glaucoma (OAG) or ocular hypertension (OHTN) who underwent a single session of 360-degree SLT between January 1, 2017 and December 31, 2018. The main outcome was mean IOP reduction and attainment of treatment success at 5 weeks and 12 weeks post treatment defined as at least 20% IOP reduction from baseline without further medications or inter-ventions. Secondary outcomes were frequency of adverse events and factors predicting success. Results: A total of 33 eyes of 33 Omani patients who underwent treatment with SLT were analyzed. The nature of response to laser followed a gradual pattern as the mean IOP reduction from baseline was 20.2% (5.21 mm Hg, P <0.001) at 5 weeks and further enhanced to 27.2% (6.95 mm Hg, P <0.001) at 12 weeks. Short-term success was achieved in 51.5% and 72.2% of eyes at 5 and 12 weeks, respectively. SLT was most effective in OHTN subgroup and those with higher baseline IOP (both P <0.001). Side effects were an infre-quent occurrence, minor and transient. Conclusion: The short-term success of SLT in Omani eyes was clinically relevant and comparable to the gradual pattern seen in patients of Indian ancestry. It is a safe therapeutic option in selective Omani eyes.
KW - Ocular hypertension
KW - Open-angle glaucoma
KW - Outcome
KW - Race
KW - SLT
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U2 - 10.2147/OPTH.S269508
DO - 10.2147/OPTH.S269508
M3 - Article
C2 - 32982156
AN - SCOPUS:85091146571
SN - 1177-5467
VL - 14
SP - 2631
EP - 2638
JO - Clinical Ophthalmology
JF - Clinical Ophthalmology
ER -