ملخص
An efficient three-step synthesis of COX-2 inhibitor inotilone from acetaldoxime is described. The structure of inotilone was elucidated via an aldol reaction between 5-methyl-3(2H)-furanone and 3,4-dihydroxybenzaldehyde. This approach describes a convenient pathway to 5-alkyl-3-furanones through isoxazole chemistry.
اللغة الأصلية | English |
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الصفحات (من إلى) | 1088-1092 |
عدد الصفحات | 5 |
دورية | Synthetic Communications |
مستوى الصوت | 40 |
رقم الإصدار | 7 |
المعرِّفات الرقمية للأشياء | |
حالة النشر | Published - يناير 2010 |
ASJC Scopus subject areas
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