Sternal abnormalities in sickle-cell disease have been documented by bone scintigraphy and radiography in patients with homozygous sickle-cell anemia, but not in patients with sickle-thalassemia. We present here two unusual cases of sternal abnormalities in complicated sickle-cell disease. One is an infant with radiographic findings of 'sternal cupping' and transient hypo- ossification of the sternum and sickle-thalassemia. The other patient is also a male infant with unusual, persistent under-ossification of bone, in association with radiographic findings of 'sternal cupping.' The second patient also had a 4P-chromosomal defect (Wolf-Hirschhorn syndrome) in which sternal hypo-ossification was described.
|الصفحات (من إلى)||1167-1169|
|دورية||Journal of Nuclear Medicine|
|حالة النشر||Published - 1994|
ASJC Scopus subject areas