Sarcoroseolides A-D, four undescribed cembranoids from the Red Sea soft coral Sarcophyton roseum

Mohammed M.A. Ahmed; Mohamed A. Albadry; Ehab A. Ragab; Elsayed M. El-Ghaly; Said K. Ismail; Zulfiqar Ali; Shabana I. Khan; Amar G. Chittiboyina; Ikhlas A. Khan

doi:10.1080/14786419.2020.1821015

Sarcoroseolides A-D, four undescribed cembranoids from the Red Sea soft coral Sarcophyton roseum

Mohammed M.A. Ahmed, Mohamed A. Albadry, Ehab A. Ragab^*, Elsayed M. El-Ghaly, Said K. Ismail, Zulfiqar Ali, Shabana I. Khan, Amar G. Chittiboyina, Ikhlas A. Khan

^*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلة › Article › مراجعة النظراء

3 اقتباسات (Scopus)

ملخص

Four undescribed cembranoids, sarcoroseolides A-D (1-4) along with nine reported related cembranoids (5-13) were isolated from the soft coral Sarcophyton roseum. The chemical structures of sarcoroseolides A-D were elucidated by extensive 1 D and 2 D NMR as well as HR-ESIMS spectroscopic data. Moreover, the geometric and absolute configurations were assigned by the modified Mosher’s method and/or NOESY experiments. The extract and the isolated metabolites were evaluated for their potential anti-inflammatory and cytotoxic activities.

اللغة الأصلية	English
الصفحات (من إلى)	1842-1850
عدد الصفحات	9
دورية	Natural Product Research
مستوى الصوت	36
رقم الإصدار	7
المعرِّفات الرقمية للأشياء	https://doi.org/10.1080/14786419.2020.1821015
حالة النشر	Published - سبتمبر 18 2020
منشور خارجيًا	نعم

ASJC Scopus subject areas

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الوصول إلى المستند

10.1080/14786419.2020.1821015

الملفات والروابط الأخرى

قم بذكر هذا

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title = "Sarcoroseolides A-D, four undescribed cembranoids from the Red Sea soft coral Sarcophyton roseum",

abstract = "Four undescribed cembranoids, sarcoroseolides A-D (1-4) along with nine reported related cembranoids (5-13) were isolated from the soft coral Sarcophyton roseum. The chemical structures of sarcoroseolides A-D were elucidated by extensive 1 D and 2 D NMR as well as HR-ESIMS spectroscopic data. Moreover, the geometric and absolute configurations were assigned by the modified Mosher{\textquoteright}s method and/or NOESY experiments. The extract and the isolated metabolites were evaluated for their potential anti-inflammatory and cytotoxic activities.",

keywords = "Sarcophyton roseum, Soft coral, cembranoids, sarcoroseolides A-D, Diterpenes/chemistry, Animals, Indian Ocean, Magnetic Resonance Spectroscopy, Molecular Structure, Anthozoa/chemistry",

author = "Ahmed, {Mohammed M.A.} and Albadry, {Mohamed A.} and Ragab, {Ehab A.} and El-Ghaly, {Elsayed M.} and Ismail, {Said K.} and Zulfiqar Ali and Khan, {Shabana I.} and Chittiboyina, {Amar G.} and Khan, {Ikhlas A.}",

note = "Publisher Copyright: {\textcopyright} 2020 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2020",

month = sep,

day = "18",

doi = "10.1080/14786419.2020.1821015",

language = "English",

volume = "36",

pages = "1842--1850",

journal = "Natural Product Research",

issn = "1478-6419",

publisher = "Taylor and Francis Ltd.",

number = "7",

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TY - JOUR

T1 - Sarcoroseolides A-D, four undescribed cembranoids from the Red Sea soft coral Sarcophyton roseum

AU - Ahmed, Mohammed M.A.

AU - Albadry, Mohamed A.

AU - Ragab, Ehab A.

AU - El-Ghaly, Elsayed M.

AU - Ismail, Said K.

AU - Ali, Zulfiqar

AU - Khan, Shabana I.

AU - Chittiboyina, Amar G.

AU - Khan, Ikhlas A.

PY - 2020/9/18

Y1 - 2020/9/18

N2 - Four undescribed cembranoids, sarcoroseolides A-D (1-4) along with nine reported related cembranoids (5-13) were isolated from the soft coral Sarcophyton roseum. The chemical structures of sarcoroseolides A-D were elucidated by extensive 1 D and 2 D NMR as well as HR-ESIMS spectroscopic data. Moreover, the geometric and absolute configurations were assigned by the modified Mosher’s method and/or NOESY experiments. The extract and the isolated metabolites were evaluated for their potential anti-inflammatory and cytotoxic activities.

AB - Four undescribed cembranoids, sarcoroseolides A-D (1-4) along with nine reported related cembranoids (5-13) were isolated from the soft coral Sarcophyton roseum. The chemical structures of sarcoroseolides A-D were elucidated by extensive 1 D and 2 D NMR as well as HR-ESIMS spectroscopic data. Moreover, the geometric and absolute configurations were assigned by the modified Mosher’s method and/or NOESY experiments. The extract and the isolated metabolites were evaluated for their potential anti-inflammatory and cytotoxic activities.

KW - Sarcophyton roseum

KW - Soft coral

KW - cembranoids

KW - sarcoroseolides A-D

KW - Diterpenes/chemistry

KW - Animals

KW - Indian Ocean

KW - Magnetic Resonance Spectroscopy

KW - Molecular Structure

KW - Anthozoa/chemistry

UR - http://www.scopus.com/inward/record.url?scp=85091061595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85091061595&partnerID=8YFLogxK

U2 - 10.1080/14786419.2020.1821015

DO - 10.1080/14786419.2020.1821015

M3 - Article

C2 - 32945198

AN - SCOPUS:85091061595

SN - 1478-6419

VL - 36

SP - 1842

EP - 1850

JO - Natural Product Research

JF - Natural Product Research

IS - 7

ER -

Sarcoroseolides A-D, four undescribed cembranoids from the Red Sea soft coral Sarcophyton roseum

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ASJC Scopus subject areas

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