TY - JOUR
T1 - Recurrent early pregnancy loss and consanguinity in Omani couples
AU - Gowri, Vaidyanathan
AU - Udayakumar, Achandira Muthappa
AU - Bsiso, Wafa
AU - Al Farsi, Yahaya
AU - Rao, Kuntal
PY - 2011/10
Y1 - 2011/10
N2 - Consanguinity is common in Arab countries. The Sultanate of Oman has a relatively small population with a high prevalence of consanguineous marriages. This is a retrospective study of women who had three or more consecutive miscarriages between January 2002 and December 2008, investigated in the non-pregnant state. Age, parity, menstrual history, number of miscarriages, personal and family history, history of consanguinity and investigations were collected for 141 patients. The mean number of miscarriages was 3.4; 53% of the women had a consanguineous marriage, 42% were non-consanguineous and in 5% the marital interrelationship was unknown. There was no significant difference in the prevalence of parental karyotype abnormalities, anticardiolipin antibodies, antinuclear antibodies, thyroid disorders, or lupus between the consanguineous and non-consanguineous couples. Consanguinity appeared not to play a significant role in the etiology of recurrent spontaneous miscarriage.
AB - Consanguinity is common in Arab countries. The Sultanate of Oman has a relatively small population with a high prevalence of consanguineous marriages. This is a retrospective study of women who had three or more consecutive miscarriages between January 2002 and December 2008, investigated in the non-pregnant state. Age, parity, menstrual history, number of miscarriages, personal and family history, history of consanguinity and investigations were collected for 141 patients. The mean number of miscarriages was 3.4; 53% of the women had a consanguineous marriage, 42% were non-consanguineous and in 5% the marital interrelationship was unknown. There was no significant difference in the prevalence of parental karyotype abnormalities, anticardiolipin antibodies, antinuclear antibodies, thyroid disorders, or lupus between the consanguineous and non-consanguineous couples. Consanguinity appeared not to play a significant role in the etiology of recurrent spontaneous miscarriage.
KW - Consanguinity
KW - Middle East
KW - etiology
KW - karyotype
KW - recurrent abortion
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U2 - 10.1111/j.1600-0412.2011.01200.x
DO - 10.1111/j.1600-0412.2011.01200.x
M3 - Article
C2 - 21623740
AN - SCOPUS:80052985505
SN - 0001-6349
VL - 90
SP - 1167
EP - 1169
JO - Acta Obstetricia et Gynecologica Scandinavica
JF - Acta Obstetricia et Gynecologica Scandinavica
IS - 10
ER -