TY - JOUR
T1 - Pyridoxine-dependent seizures
T2 - 10-year follow-up of eight cases
AU - Koul, Roshan
PY - 2009/10/1
Y1 - 2009/10/1
N2 - Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in childrens younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyridoxine.
AB - Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in childrens younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyridoxine.
KW - Neonatal status epilepticus
KW - Pyridoxine
KW - Pyridoxine dependency
KW - Refractory seizures
UR - http://www.scopus.com/inward/record.url?scp=70349427305&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349427305&partnerID=8YFLogxK
U2 - 10.4103/0028-3886.55595
DO - 10.4103/0028-3886.55595
M3 - Article
C2 - 19770548
AN - SCOPUS:70349427305
SN - 0028-3886
VL - 57
SP - 460
EP - 463
JO - Neurology India
JF - Neurology India
IS - 4
ER -