TY - CHAP
T1 - Protein Nutrition in Autism
AU - Chidambaram, Saravana Babu
AU - Bhat, Abid
AU - Mahalakshmi, Arehally Marappa
AU - Ray, Bipul
AU - Tuladhar, Sunanda
AU - Sushmitha, B. S.
AU - Saravanan, B.
AU - Thamilarasan, Manivasagam
AU - Thenmozhi, Arokiasamy Justin
AU - Essa, Musthafa Mohamed
AU - Guillemin, Gilles J.
AU - Qoronfleh, M. Walid
N1 - Publisher Copyright:
© 2020, Springer Nature Switzerland AG.
PY - 2020
Y1 - 2020
N2 - Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.
AB - Autism is a developmental disorder that affects communication and behavior. Although autism can be diagnosed at any age, it is said to be a “developmental disorder” because symptoms generally appear in the first 2 years of life. The primary cause of autism is still not clear and therapy is currently restricted to controlling behavioral abnormalities. However, emerging studies have shown a link between mitochondrial dysfunction and autism. Dietary supplements that promote mitochondrial biogenesis and inhibit the production of oxidative stress have been used to treat autism patients. Dietary adjustments in treating autism is a novel approach to suppress autistic symptoms. Supplementation with antioxidants has been found to not only inhibit cognitive decline but also improve behavioral symptoms in autism. Dietary supplements fortified with vitamins should only be given under the supervision of a physician. A wide range of nutraceuticals are under clinical trials to understand whether they physiologically target mitochondrial pathways and improve the quality of life in autism.
KW - Amino acids
KW - ASD
KW - Autism
KW - Dietary therapy
KW - Gluten-free, casein-free (GFCF) diet
KW - Malabsorption
KW - Mitochondrial dysfunction
KW - Nutritional imbalance
KW - Peptides
KW - Protein maldigestion
KW - Autistic Disorder/diet therapy
KW - Humans
KW - Oxidative Stress/drug effects
KW - Dietary Proteins/therapeutic use
KW - Mitochondria/drug effects
KW - Quality of Life
KW - Diet Therapy
KW - Dietary Supplements
UR - http://www.scopus.com/inward/record.url?scp=85078862779&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85078862779&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/e09c346e-be92-323f-8a21-4694304eedce/
U2 - 10.1007/978-3-030-30402-7_20
DO - 10.1007/978-3-030-30402-7_20
M3 - Chapter
C2 - 32006374
AN - SCOPUS:85078862779
VL - 24
T3 - Advances in neurobiology
SP - 573
EP - 586
BT - Advances in Neurobiology
PB - Springer
ER -